Table 3. Overall and Comorbidity-Free Life Expectancy at Age 21 Years for Individuals With and Without HIV Infection and for Individuals With HIV Infection Who Initiated ART at High CD4 Cell Counts, Kaiser Permanente, 2011-2016.
| Outcome | Life expectancy at age 21 y, No. of y (95% CI) | ||||||
|---|---|---|---|---|---|---|---|
| Individuals with HIV infection | Individuals with HIV infection with CD4 cell count ≥500/μL at ART initiation | Individuals without HIV infection | Difference | ||||
| Individuals with HIV infection vs individuals without HIV infection | Individuals with HIV infection with CD4 cell count ≥500/μL at ART initiation vs Individuals without HIV infection | ||||||
| Overall | 54.9 (54.0 to 55.9) | 57.4 (55.7 to 59.1) | 64.2 (64.0 to 64.4) | 9.2 (8.3 to 10.2) | 6.8 (5.0 to 8.5) | ||
| Comorbidity freea | 13.7 (13.0 to 14.4) | 19.5 (17.8 to 21.2) | 29.0 (28.6 to 29.3) | 15.3 (14.5 to 16.1) | 9.5 (7.7 to 11.2) | ||
| Chronic disease | |||||||
| Liver | 33.1 (31.9 to 34.2) | 42.5 (39.8 to 45.1) | 57.6 (57.3 to 57.9) | 24.5 (23.3 to 25.7) | 15.1 (12.5 to 17.8) | ||
| Kidney | 40.2 (39.5 to 41.0) | 42.5 (40.8 to 44.2) | 56.3 (56.0 to 56.5) | 16.1 (15.3 to 16.9) | 13.8 (12.0 to 15.5) | ||
| Lung | 23.4 (22.3 to 24.6) | 31.3 (28.5 to 34.1) | 38.5 (38.0 to 38.9) | 15.0 (13.7 to 16.3) | 7.2 (4.3 to 10.0) | ||
| Diabetes | 44.2 (43.2 to 45.3) | 50.2 (47.9 to 52.4) | 51.7 (51.3 to 52.0) | 7.4 (6.4 to 8.5) | 1.5 (−0.8 to 3.8) | ||
| Cancer | 48.1 (47.0 to 49.1) | 52.6 (50.3 to 54.8) | 58.0 (57.7 to 58.2) | 9.9 (8.8 to 11.0) | 5.4 (3.1 to 7.7) | ||
| Cardiovascular disease | 51.8 (50.9 to 52.7) | 56.4 (54.3 to 58.5) | 60.8 (60.5 to 61.0) | 9.0 (8.0 to 9.9) | 4.4 (2.2 to 6.5) | ||
Abbreviation: ART, antiretroviral therapy.
a
Comorbidity-free years were those lived before incident diagnosis of any of the 6 common comorbidities.