Table 3. Pooled Hazard Ratios of Cardiovascular Disease According to the 4 Dietary Scores Across Racial/Ethnic Groups in the Nurses’ Health Study and Nurses’ Health Study IIa.
Variableb | Cases/person-years | HR (95% CI) | P value for interactionc |
---|---|---|---|
HEI-2015 | |||
Non-Hispanic white | 11 793/4 068 772 | 0.68 (0.64-0.72) | NA |
Minority racial/ethnic group | 798/288 861 | 0.71 (0.55-0.91) | .74 |
Non-Hispanic black | 144/52 982 | 0.62 (0.33-1.15) | .77 |
Hispanic | 92/55 008 | 0.48 (0.22-1.07) | .39 |
Other | 562/180 871 | 0.77 (0.58-1.03) | .41 |
AMED | |||
Non-Hispanic white | 11 793/4 068 772 | 0.80 (0.77-0.84) | NA |
Minority racial/ethnic group | 798/288 861 | 0.79 (0.68-0.92) | .88 |
Non-Hispanic black | 144/52 982 | 0.86 (0.59-1.27) | .71 |
Hispanic | 92/55 008 | 0.74 (0.46-1.20) | .75 |
Other | 562/180 871 | 0.78 (0.66-0.93) | .78 |
HPDI | |||
Non-Hispanic white | 11 793/4 068 772 | 0.78 (0.74-0.83) | NA |
Minority racial/ethnic group | 798/288 861 | 0.70 (0.55-0.89) | .39 |
Non-Hispanic black | 144/52 982 | 0.76 (0.41-1.40) | .93 |
Hispanic | 92/55 008 | 0.82 (0.40-1.68) | .89 |
Other | 562/180 871 | 0.67 (0.51-0.89) | .30 |
AHEI | |||
Non-Hispanic white | 11 793/4 068 772 | 0.70 (0.66-0.74) | NA |
Minority racial/ethnic group | 798/288 861 | 0.72 (0.58-0.88) | .80 |
Non-Hispanic black | 144/52 982 | 0.78 (0.45-1.34) | .70 |
Hispanic | 92/55 008 | 0.50 (0.26-0.98) | .32 |
Other | 562/180 871 | 0.74 (0.58-0.94) | .66 |
Abbreviations: AHEI, Alternate Healthy Eating Index; AMED, Alternate Mediterranean Diet Score; HEI-2015, Healthy Eating Index–2015; HPDI, Healthful Plant-Based Diet Index; HR, hazard ratio; NA, not applicable.
Results from the Nurses’ Health Study (NHS) and the NHS II were pooled using the fixed-effect model with inverse-variance weighting per 25-percentile increment in the 4 dietary scores (25 points for the HEI-2015, 9 points for the AMED, 18 points for the HPDI, and 25 points for the AHEI). Multivariable analysis adjusted for age, body mass index, physical activity, smoking status, alcohol intake, menopausal status, oral contraceptive use (NHS II only), calendar year marital status, living alone or with others, family history of myocardial infarction, total energy intake, multivitamin use, aspirin use, and family history of diabetes.
Non-Hispanic white includes non-Hispanic women with southern European/Mediterranean ancestry, Scandinavian ancestry, and other Caucasian ancestry. Minority racial/ethnic groups include non-Hispanic black, Hispanic, and other racial/ethnic women. Other includes women not classified as non-Hispanic white, non-Hispanic black, or Hispanic, such as Asian and American Indian.
Interaction between non-Hispanic white and total minority racial/ethnic group or individual racial/ethnic group.