(A) Schematic
diagram depicting glycerophospholipids metabolism
in P. aeruginosa FADDI-PA111 and (B) bar charts for
the significantly impacted metabolites involved in glycerophospholipids
metabolism of FADDI-PA111 and FADDI-PA006 following treatment with
polymyxin B (PMB, green), ivacaftor (IVA, blue), and their combination
(COM, red) (≥1.0-log2-fold, p ≤
0.05; FDR ≤ 0.05). Data represent geometric means of relative
intensity ± standard deviation (n = 4).