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FPT is an anticonvulsant in Fmr1 knockout mice. The majority of vehicle-treated Fmr1 knockout mice (ages P23–P25) had lethal audiogenic seizures. FPT blocked audiogenic seizures in all mice tested; results were highly significant (****, P < 0.0001, relative to vehicle). WRJ = wild running and jumping. Non-lethal seizure = recovered from tonic-clonic seizure.
