Fig. 4.

Principle co-ordinate ordination of the bacterial communities from paired DFU swab and tissue biopsies. A Bray Curtis similarity matrix was generated from 4th root-transformed OTUs. Vector overlay is based on Pearson correlation (r ≥ 0.8) with the specific bacteria listed that correspond to the vectors in each direction. Relative abundances of bacterial communities contributing to the disparity along PCO2 were equal to or less than 1% of total reads (Supplementary Table S4 Additional File 2)