Table 5.
Factors influencing morbidity and mortality on bivariate logistic regression of patients with perforated Peptic ulcer disease in four teaching hospital in Addis Ababa, Ethiopia
| Variable | Complications N (%) N = 16 |
No Complications N (%) N = 68 |
P-value | Death N (%) N = 3 |
Discharged improved N (%) N = 94 |
P-value | |
|---|---|---|---|---|---|---|---|
| Sex | Male | 16 (19.04) | 68 (80.1) | 3(3.6) | 81(96.4) | ||
| Female | 0 (0) | 13(100) | 0.136 | 0 | 13 | 0.787 | |
| Age | 11–20 | 3 (17.6) | 14 (82.4) | 0 (0) | 17(100) | ||
| 21–30 | 4(9.8) | 37 (90.2) | 0(0) | 41(100) | |||
| 31–40 | 4 (17.4) | 19 (82.6) | 2 (8.7) | 21(91.3) | |||
| 41–50 | 1 (25) | 3 (75) | 0(0) | 4 (100) | |||
| 51–60 | 1 (16.7) | 5 (83.3) | 0 (0) | 6(100) | |||
| 61–70 | 2 (50) | 2 (50) | 1(25) | 3(75) | |||
| 71–80 | 1 (50) | 1 (50) | 0.08 | 0(0) | 2 (100) | 0.003 | |
| Address | AA | 12 (14.6) | 70(85.4) | 3 (3.6) | 79(96.4) | ||
| Outside | 4 (26.7) | 11(73.3) | 0.391 | 0 (0) | 15(100) | 0.475 | |
| Religion | Orthodox | 11(14.9) | 63(85.1) | 2 (2.7) | 73 (98.3) | ||
| Muslim | 4(25) | 12(75) | 1 (6.3) | 15 (93.7) | |||
| Others Christians | 0(0) | 6(100) | 0.310 | 0 (0) | 6 (100) | 0.746 | |
| History of PUD | History of PUD | 13 (17.8) | 60 (82.2) | 3 (4.1) | 70 (95.90 | ||
| No history of PUD | 3 (12.50 | 21(87.50 | 0 (0) | 24(100) | 0.337 | ||
| Smoking | Yes | 5 (15.6) | 27(84.40) | 0 (0) | 32(100) | ||
| No | 11(16.9) | 54 (84.10 | 0.922 | 3 (4.6) | 62 (95.4) | 0.240 | |
| Alcohol | Yes | 4 (16.4) | 38(83.6) | 0 (0) | 44 (100) | ||
| No | 10 (18.70) | 43 (81.3) | 0.212 | 0.126 | |||
| Khat use/Catha edulis | Yes | 2 (12.5) | 14 (87.5) | 1(5.9) | 16 (94.1) | ||
| NO | 15 (18.5) | 66 (81.5) | 0.141 | 2 (2.5) | 78 (97.5) | 0.323 | |
| Co-morbidity | Yes | 0 (0) | 3 (100) | 1(33.3) | 2 (66.70 | ||
| 16 (17) | 78(83) | 0.00 | |||||
| NSAID use | yes | 1 (50) | 1(50) | 0 (0) | 2 (100) | ||
| No | 15 (15.8) | 80 (84.2) | 0.076 | 3 (3.2) | 92(96.8) | 0.809 | |
| Hx of PUD | Yes | 13(17.8) | 60 (82.2) | 3 (4.1) | 70 (95.9) | ||
| No | 3 (12.5) | 21(87.5) | 0.139 | 0 | 0 | ||
| H.Pylri infection | Present | 1 (33.3) | 2 (66.7) | 0.647 | 1 (33.3) | 2 (66.70 | 0.02 |
| Duration at presentation | < 24 h. | 4 (9) | 40 (91) | 0(0) | 44 (100) | ||
| 24–48 h. | 5 (15.1) | 28 (84.9) | 1 (3) | 32 (97) | |||
| 48–72 h. | 3 (27.3) | 7(72.7) | 0(0) | 10 (100) | |||
| > 72 h. | 4 (40) | 6 (60) | 0.004 | 2 (20) | 8 (80) | 0.003 | |
| WBC count | Raised | 7 (15.6) | 38 (84.4) | 0 (0) | 45 (100) | ||
| Normal | 9 (17.3) | 43 (82.7) | 0.610 | 3 (5.8) | 49 (94.2) | ||
| CXR finding | Free air | 14 (16.7) | 69 (83.3) | 2 (2.4) | 81(97.6) | ||
| Not detected | 1(9.1) | 10 (90.9) | 0 (0) | 11(100) | |||
| Not done | 1 (33.3) | 2 (66.7) | 1 (33.3) | 2 (66.7) | |||
| Hypotension | Yes | 9 (52.9) | 8 (47.1) | 0.000 | 3 (17.6) | 14 (82.4) | 0.001 |
| Perforation size | < 10 mm | 7 (9.2) | 69 (90.8) | 0 (0) | 79 (100) | ||
| 10-20 mm | 5 (41.7) | 7 (59.3) | 1 (8.3) | 11(91.7) | |||
| > 20 mm | 1 (50) | 1 (50) | 2 (100) | 0 (0) | 0.000 | ||
| Sealed | 0 (0) | 4 (100) | 0,046 | 0 (0) | 1(100) | ||
| contamination | < 1 Lts | 7 (9.7) | 65 (90.3) | 1 (1.4) | 71 (98.6) | ||
| 1–3 Lts | 7 (33.3) | 14 (66.7) | 1 (4.8) | 20 (95.2) | |||
| > 3 Lts | 1 (33.3) | 2 (66.7) | 0.000 | 1 (25) | 3 (75) | 0.006 | |
| Procedure done | Simple closure | 0 (0) | 0 (0) | 0 (0) | 0 (0) | ||
| Pedicled omental | 11(16.9) | 54 (83.1) | 3 (4.6) | 62(95.4) | |||
| Free omental | 5 (18.5) | 23 (81.5) | 0.399 | 0 (0) | 27 (100) | ||
| Drainage left | 15 (16.8) | 74 (83.2) | 3 (3.4) | 86 (96.6) |