Fig. 4.

Changes in NK cell subsets in whole blood. a FACS gating strategy used to identify CD3-CD56+ total NK cells, CD3-CD56^bright NK cells, and CD3+CD56+ NKT cells. b Total CD3-CD56+ NK cells. c CD3-CD56^bright NK cells. d CD3+ CD56+ NKT cells. e Ratio of NKT cells:CD3-CD56^bright T cells. Data represent median/IQR values for all patients at each timepoint; open circles indicate data points for each individual patient. p values indicate significant changes from baseline (M0) values as follows: ****p ≤ 0.0001, ***p ≤ 0.001, **p ≤ 0.01, *p ≤ 0.05; mixed effects ANOVA with Tukey’s corrections for multiple comparisons