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. 2020 Jun 11;14:2335–2353. doi: 10.2147/DDDT.S249093

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© 2020 Hassan et al.

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GLM modulates hepatic inflammatory response. Effects of GLM (500 mg/kg/day) on hepatic levels of (A) HMGB-1, (B) TNF-α, and (C) IL-10 in CP-induced liver injury in rats. Data are expressed as means ± SEM. Statistically significant differences when p<0.05 indicated as: ^$$$compared to control group P<0.001; ^€€€compared o GL group P<0.001; ***compared to CP group P<0.001; **compared to CP group P<0.01. *compared to CP group P<0.05.

Abbreviations: GLM, Ganoderma lucidum mushroom; HMGB-1, high-mobility group box-1, TNF-α, tumor necrosis factor-alpha; IL-10, interleukin-10; CP, cisplatin; GL, Ganoderma lucidum group.