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. Author manuscript; available in PMC: 2021 Jun 1.
Published in final edited form as: J Struct Biol. 2020 Apr 10;210(3):107506. doi: 10.1016/j.jsb.2020.107506

Figure 2. Dodecamer of BtSpeG produces three binding interfaces.

Figure 2.

A, Biological unit of BtSpeG is composed of a dimer of hexamers with D6 symmetry. Larger letters correspond to the monomers on the top face of the hexamer and the smaller letters correspond to monomers on the bottom face of the hexamer. Three interfaces mediate assembly of the dodecameric biological unit with two hexamers stacked on top of each other with D6 symmetry. B, schematic representation of dodecameric assembly of BtSpeG. C, Schematic representation of the four monomers that produce the 3 binding interfaces involved in biological unit assembly with schematic representation. The type I interface is between neighboring monomers of the same hexamer (A/B) and (A/ F). The type II interface is formed between monomers (A/ G) of opposing hexamers. The type III interface is formed between diagonal adjacent partners of the opposing hexamers.