Table 3.
Independent risk factors for disease-free survival in NSCLC patients (n=99).
| Variable | Univariate | Multivariate analysis | ||
|---|---|---|---|---|
| P-value | P-value | Hazard ratio (95% CI) | ||
| Size of tumor (cm) | ≥4 vs. <4 | 0.002 | ||
| TNM stage | I–II vs. III–IV | 0.001 | 0.001 | 1.538 (1.299–2.984) |
| Lymph node metastasis | Negative vs. positive | 0.003 | ||
| CYFRA21-1 | <3.3 vs. ≥3.3 | 0.005 | 0.023 | 1.328 (1. 436–3.182) |
| CEA | <5 vs. ≥5 | 0.003 | ||
| Exo-eIF4E | <6.23 vs. ≥6.23 | 0.001 | 0.005 | 1.478 (1.134–2.972) |
NSCLC – non-small cell lung cancer; CI – confidence interval; CYFRA21-1 – cytokeratin fragment 19; CEA – carcinoembryonic antigen; Exo-eIF4E – eoxsomal eIF4E.