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Methane-rich saline inhibited the endoplasmic reticulum stress signaling pathway in DSS-induced inflammatory bowel diseases. (A) Western blot assay of CHOP, ATF4, GRP78, and caspase-12 in colon tissues and (B) relative band intensity. (* P<0.05, ** P<0.01, *** P<0.001 as compared with the DSS+NS group). DSS – dextran sulfate sodium; NS – normal saline.
