TABLE 4.

Relative Hazards of Mortality Among Women In the Women’s Health Initiative Diagnosed With Colorectal Cancer, by Cancer Site^a

Characteristicb	HR (95% CI)
	Colon Cancer	Rectal Cancer
No. of women	1168	183
Overall mortality, no.	445	68
Level of social integration
Socially integrated	1.00	1.00
Moderately integrated	1.25 (0.96–1.63)	1.82 (0.82–4.06)
Socially isolated	1.32 (1.00–1.74)	2.61 (1.15–5.92)
P for trend	.05	.006
P for interaction	.29
Living situation
Lives with someone	1.00	1.00
Lives alone	0.98 (0.79–1.22)	1.81 (1.01–3.25)
P-value	.87	.05
P for interaction	.02
CRC-specific mortality, no.	273	41
Level of social integration
Socially integrated	1.00	1.00
Moderately integrated	1.25 (0.89–1.75)	2.28 (0.83–6.26)
Socially isolated	1.28 (0.89–1.84)	3.43 (1.17–10.0)
P for trend	.22	.05
P for interaction	.65
Living situation
Lives with someone	1.00	1.00
Lives alone	0.93 (0.70–1.24)	1.76 (0.77–4.01)
P for trend	.61	.18
P for interaction	.03

Abbreviations: CRC, colorectal cancer; HR, hazard ratio.

^aNo difference was observed in the association between social support and outcomes by cancer site.

^bModels were adjusted for age at diagnosis (continuous), time between social assessment and diagnosis (continuous), study (clinical trial, observational study), race/ethnicity (non-Hispanic white [reference category], African-American, Asian/Pacific Islander, Hispanic, other), and stage and grade (local [reference category], regional, distant and well differentiated/moderately differentiated, distant and nondifferentiated/anaplastic), site (rectal, colon [reference category]), education (<high school, high school, some college, college degree or greater [reference category]), income (<$20,000, $20,000 to <$50,000, ≥$50,000 [reference category]), family history of colorectal cancer (yes, no [reference category]), and comorbidity (yes, no [reference category]).