Table 1.

Consensus research framework criteria for posterior cortical atrophy (2).

Core Clinical Features: All three must be present	•Insidious onset •Gradual progression •Prominent early disturbance of visual functions, other posterior cognitive functions, or both
Core Cognitive Features: At least three must be present as an early or presenting feature	Space perception deficit, simultanagnosia, object perception deficit, constructional dyspraxia, environmental agnosia, oculomotor apraxia, dressing apraxia, optic ataxia, alexia, left/right disorientation, acalculia, limb apraxia (not limb-kinetic), apperceptive prosopagnosia, agraphia, homonymous visual field defect, finger agnosia
Core Neuroimaging Features: Supportive of diagnosis	Predominant occipitoparietal or occipitotemporal atrophy or hypometabolism or hypoperfusion on MRI, FDG-PET, or SPECT
Non-posterior Cortical Features: All of the following must be evident	•Relatively spared anterograde memory function •Relatively spared speech and non-visual language functions •Relatively spared executive functions •Relatively spared behavior and personality
Exclusions:	•No afferent visual dysfunction or afferent lesions to explain symptoms •No vascular lesions to explain symptoms •No brain tumor or other mass lesion to explain symptoms •No evidence of other causes to explain symptoms