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. 2020 Jun 12;13:1953–1967. doi: 10.2147/DMSO.S243170

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© 2020 Ndibalema et al.

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Effect of empagliflozin on the expression of proteins related to EMT in HK-2 cell line. HK-2 cells were planted in 5.5mM glucose and 25mM glucose with or without empagliflozin treatment under normoxia for 72 h. (A) Western blotting was performed using anti-α-SMA, anti-E-cadherin, and anti-β-actin antibodies. β-actin used as a loading control. (B-C) Quantification of Western blot data. (D–E) Individual measurements represented as dot plots. The data represent the mean ± SD of three independent experiments., **P < 0.01, ***P < 0.001, vs. high glucose.

Abbreviation: ns, non-significant.