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. 2020 Jun 16;15(6):e0234731. doi: 10.1371/journal.pone.0234731

Fig 5. Chemical mediator mRNA and transcription factor expression in sinonasal mucosa of Alternaria induced Chronic RhinoSinusitis (CRS) mouse model.

Fig 5

IL-4 and IFN-γ and their transcription factor mRNA expression were significantly increased non-allergic CRS group at 8 weeks. IL-10 and its transcription factor mRNA expression were significantly increased both allergic and non-allergic CRS group at 8 weeks (3–4 mice per group). NC: negative control, ALTwOVA: Alternaria instillation with ovalbumin (OVA) presensitization, ALTsOVA; Alternaria instillation without ovalbumin (OVA) presensitization. *p<0.05 vs NC group, †p<0.05 vs with or without OVA group.