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Effect of EA and urolithins (conjugated and free forms) on eicosanoid biosynthesis in stimulated human leukocytes. The bar charts show the level of PGE2 (A), 5-HETE (B), LTB4 (C), HKE2 (D), and HKD2 (E) quantified using LC-MS/MS analysis after AMPP-derivatization. The dashed red horizontal line indicates the concentration quantified in stimulated leukocytes. The results are shown as average ± standard deviation (SD) of six volunteers. Each treatment was analyzed in duplicate.
