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. Author manuscript; available in PMC: 2021 Jun 1.
Published in final edited form as: Mol Nutr Food Res. 2020 May 4;64(11):e2000129. doi: 10.1002/mnfr.202000129

Figure 5.

Figure 5.

Dose-dependent effect of Uro-A, IsoUro-A, and Uro-C on hemiketal (HK) formation by the 5-LOX/COX-2 cross-over pathway in stimulated human leukocytes. HKE2 (A) and HKD2 (B) were quantified using LC-MS/MS analysis after AMPP-derivatization. The box plots show the range of data between the 25th and 75th percentiles. Veh., vehicle. Solid horizontal line within bars: median. Dash horizontal line: mean. (SD) from 6 volunteers. Each treatment was analyzed in duplicate. *p<0.05, ***p<0.001 compared to the stimulated/veh.-treated group.