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. Author manuscript; available in PMC: 2021 Jul 1.
Published in final edited form as: Dev Biol. 2020 May 4;463(1):77–87. doi: 10.1016/j.ydbio.2020.04.007

Figure 3: IGF1R-infected primary mouse MECs demonstrate hyperplastic, highly differentiated outgrowths resulting in attenuated reconstitution.

Figure 3:

A) Reconstituted glands of wild-type MECs infected with empty vector control (n=7) or CD8-IGF1R lentivirus (n=6). B) Demonstrating ZSGreen and carmine stained mammary outgrowths; 4x and 10x, respectively. C) H&E staining; 4x with 20x insets. D) IF of 15,000 cell reconstituted tumors (n=2) co-stained with K8 (green), K14 (red), and IGF1R (purple).