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. 2020 Jun 3;182(2):389–399. doi: 10.1007/s10549-020-05711-5

Table 1.

Patient characteristics

LDMC CCT p
n = 40 n = 80
Median age at start of therapy (range) (years) 63 (35–83) 61 (30–81) 0.230
Median age at FD MBC (range) (years) 59 (33–82) 59 (28–81) 0.544
Median age at FD BC (range) (years) 51 (29–80) 52 (26–79) 0.506
Age at start of therapy
 Younger 20 (50.0%) 40 (50.0%) 1.000
 Elderly 20 (50.0%) 40 (50.0%)
Chemotherapy line
 Non-heavily pretreated 21 (52.5%) 42 (52.5%) 1.000
 Heavily pretreated 19 (47.5%) 38 (47.5%)
Metastatic sites
 No multiple metastases 25 (62.5%) 50 (62.5%) 1.000
 Multiple metastases 15 (37.5%) 30 (37.5%)
HR status
 HR-positive 30 (75.0%) 60 (75.0%) 1.000
 Triple-negative 10 (25.0%) 20 (25.0%)

LDMC low-dose metronomic chemotherapy, CCT conventional chemotherapy, FD first diagnosis, MBC metastatic breast cancer, BC breast cancer, HR hormone receptor