Fig. 1.

Immunohistochemical expression of MMP9 in BC. Morphological characteristics of MMP9 immunohistochemistry in Full-face breast cancer tissue (a–f). a Normal mammary gland and b DCIS showing absent or weak MMP9 staining. Showing high immunoreactivity in c invasive, and d LVI positive tumour samples. Showing high MMP9 stromal staining (e) and (f) no primary antibody control (negative control) in invasive breast carcinoma. All images are at 50 µm. MMP9 protein expression in breast cancer TMA cores (g) and (h) showing low and high cytoplasmic (C+) expression while, i and j showing low and high stromal (S+) expression, respectively. The normal kidney tissue (k) section used as positive control. TMA cores are 100 µm magnification