Table 4.

Multivariate analysis and risk score

	Multivariate Model 1: Compulsive insertion method						Multivariate Model 2: Variable-increasing method using likelihoods						Score ratio	Score (point)
	B	SE	HR	HR (95% CI upper lower)		p value	B	SE	HR	HR (95% CI upper lower)		p value
Age
< 70	Ref						Ref
≥ 70	0.850	0.191	2.340	1.610	3.400	< 0.001	0.850	0.191	2.340	1.610	3.400	< 0.001	2.193	2
Tumor stage
T1	Ref						Ref
T2–4	0.584	0.175	1.793	1.273	2.526	0.001	0.584	0.175	1.793	1.273	2.526	0.001	1.507	2
TX Tis T0	− 0.086	0.726	0.917	0.221	3.804	0.905	−  0.086	0.726	0.917	0.221	3.804	0.905
Nodal status
N0	Ref						Ref
N1–3	0.388	0.162	1.473	1.073	2.023	0.016	0.388	0.162	1.473	1.073	2.023	0.016	1.000	1
NX	1.053	1.013	2.866	0.393	20.883	0.299	1.053	1.013	2.866	0.393	20.883	0.299
Tumor size (pathological)
< 1 cm	Ref						Ref
≥ 1 cm	0.485	0.169	1.623	1.166	2.260	0.004	0.485	0.169	1.623	1.166	2.260	0.004	1.250	1
Lymph node metastasis
n0	Ref						Ref
n1	0.224	0.172	1.251	0.894	1.752	0.192	0.224	0.172	1.251	0.894	1.752	0.192
n2–3	0.780	0.188	2.182	1.511	3.151	< 0.001	0.780	0.188	2.182	1.511	3.151	< 0.001	2.013	2
Preoperative systemic therapy
No	Ref						Ref
Yes	0.570	0.158	1.769	1.297	2.412	< 0.001	0.570	0.158	1.769	1.297	2.412	< 0.001	1.472	1

B regression coefficient, SE regression coefficient of regression coefficient, HR hazard ratio, 95% CI 95% confidence interval, ref reference