Table 2.
Variable | DFS rates | OS rates | ||||
---|---|---|---|---|---|---|
No. of events | % | Log-rankap-value | No. of events | % | Log-rankap-value | |
MetS | 0.008 | < 0.0001 | ||||
No | 109 | 79.8 | 48 | 91.1 | ||
Yes | 49 | 71.2 | 41 | 75.9 | ||
No. of MetS comp.b | 0.02 | < 0.0001 | ||||
0 components | 24 | 80.2 | 5 | 98.9 | ||
1–2 components | 68 | 79.2 | 39 | 88.1 | ||
3–5 components | 49 | 71.2 | 41 | 75.9 | ||
Age | 0.1 | < 0.0001 | ||||
≤ 55 years | 78 | 79.8 | 26 | 93.3 | ||
> 55 years | 80 | 75.2 | 63 | 80.5 | ||
Stage | < 0.0001 | < 0.0001 | ||||
I–II | 100 | 82.1 | 456 | 90.0 | ||
III | 46 | 62.0 | 30 | 75.2 | ||
IHC-subtypes | 0.001 | 0.04 | ||||
Luminal A | 52 | 81.2 | 32 | 88.4 | ||
Luminal B | 41 | 79 | 24 | 87.7 | ||
HER2 positive | 36 | 70 | 16 | 86.7 | ||
Triple negative | 25 | 72.8 | 16 | 82.6 | ||
Therapy | < 0.0001 | < 0.0001 | ||||
Chemotherapy only | 32 | 69.5 | 22 | 79.0 | ||
Hormone only | 34 | 86.6 | 22 | 91.3 | ||
Chemo + hormone | 70 | 78.0 | 29 | 90.9 | ||
HOMA-IR score | 0.9 | 0.1 | ||||
Normal (< 2.6) | 83 | 77.3 | 51 | 86.1 | ||
Medium (2.6–5) | 26 | 81.9 | 10 | 93.1 | ||
High (> 5) | 19 | 71.2 | 8 | 87.9 | ||
Waist circumference | 0.1 | < 0.0001 | ||||
≤ 88 cm | 72 | 79.8 | 30 | 91.6 | ||
> 88 cm | 84 | 75.5 | 58 | 83.1 | ||
Blood pressure | 0.8 | 0.03 | ||||
< 130; < 85 mmHg | 80 | 78.1 | 40 | 89.0 | ||
≥ 130; ≥ 85 mmHg | 64 | 77.5 | 47 | 83.5 | ||
HDL | 0.1 | 0.04 | ||||
≥ 50 mg/dL | 93 | 77.6 | 52 | 87.5 | ||
< 50 mg/dL | 37 | 72.6 | 26 | 80.7 | ||
Triglycerides | < 0.0001 | < 0.0001 | ||||
< 150 mg/dL | 110 | 80.8 | 44 | 92.3 | ||
≥ 150 mg/dL | 45 | 62.8 | 43 | 64.2 | ||
Fasting glucose | 0.003 | 0.001 | ||||
< 110 mg/dL | 123 | 79.2 | 64 | 89.2 | ||
≥ 110 mg/dL | 34 | 70.2 | 25 | 78.1 |
aKaplan–Meier univariate analysis
bNCEP—ATP III criteria