Fig. 5.
Effect of NGR-Dau conjugates 1 and 2 (10 mg/kg Dau content, 11 treatments, black arrows) and free Dau (1 mg/kg, 5 treatments, red arrows) on subcutaneous Kaposi’s sarcoma bearing mice. a Animal body weight (g, average ± SEM). b Tumor volume (mm3, average ± SEM). c Liver/body weight ratio (percentage, average ± SEM) after termination of experiment, 70 days after cell inoculation, 5 animals per group. Statistical analysis was performed by Mann-Whitney test. * means significantly different at p < 0.05