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Effect of NGR-Dau conjugates 1 and 2 and free Dau on proliferation in primary tumor in Kaposi’s sarcoma (a) and HT-29 human colon carcinoma (b) bearing mice. Effect of NGR-Dau conjugates 1 and 2 and free Dau on vascularization in primary tumor in Kaposi’s sarcoma (c) and HT-29 human colon carcinoma (d) bearing mice. Values represent average ± SEM. Statistical analysis was performed by Mann-Whitney test. * and ** mean significant at p < 0.05 and p < 0.01, respectively
