Table 2.

Median baseline alpha diversity measures^a by select tumor characteristics and breast cancer risk factors

	N	Observed species	Chao1	Shannon	PD tree
Age
< 50	20	37.50	69.05	3.07	12.65
50+	17	35.00	66.00	3.00	11.97
p value		0.39	0.43	0.86	0.17
Stage
I/II	22	34.00	56.06	2.98	11.79
III	15	35.00	68.50	2.98	11.97
p valueb		0.84	0.80	0.38	0.65
Grade
I/II	14	31.00	54.00	2.97	11.46
III	23	36.50	67.33	2.99	12.30
p valueb		0.25	0.40	0.46	0.33
ER status
Positive	28	33.50	60.86	2.97	11.72
Negative	9	36.00	66.00	2.99	12.62
p valueb		0.64	0.87	0.53	0.36
PR status
Positive	23	33.50	57.49	2.97	11.72
Negative	14	36.00	68.50	2.99	12.62
p valueb		0.93	0.93	0.93	0.62
HER2 status
Positive	12	26.00	53.00	2.71	10.88
Negative	25	36.50	69.17	3.07	12.42
p valueb		0.033	0.073	0.035	0.11
BMI (kg/m2)
< 25	9	38.00	71.58	3.12	12.49
≥ 25	28	33.00	58.13	2.92	11.97
p valueb		0.091	0.24	0.11	0.33
Total body fat (TBF)
≤ 46%	25	36.52	72.41	3.03	12.11
> 46%	12	31.17	49.99	2.91	11.05
p valueb		0.059	0.011	0.35	0.26
BMI &TBF
I (< 25 & ≤ 46)	9	38.56	74.67	3.16	12.34
II (≥ 25 & ≤ 46)	16	35.38	71.13	2.96	11.97
III (≥ 25 & > 46)	12	31.17	49.99	2.91	11.05
p (2df)		0.11	0.038	0.38	0.50
Age menarche
≤ 11	11	29.18	50.51	2.73	10.25
≥ 12	26	35.38	69.74	3.00	11.89
p valueb		0.034	0.020	0.057	0.073
Livebirths
None	8	35.5	51.8	3.04	11.72
1+	29	33.0	66.0	2.89	12.11
p valueb		0.81	0.77	0.91	0.71
Physical activityc
No	13	34.00	48.75	3.11	12.53
Yes	24	37.00	69.17	3.00	12.30
p valueb		0.58	0.07	0.82	0.31

^aRarefaction of 100

^bp obtained by Wilcoxon rank sum test

^cNo strenuous, vigorous or moderate activity per week