Table 5.
Mean estimate ratios (MER)a obtained by zero-inflated negative binomial model of taxa abundances by age groupb, menarche age and parityc
| Age (≤ 50 vs 50+)b | Menarche Agec ≤ 11 vs ≥ 12 |
Nulliparous vs Parousc | ||||||
|---|---|---|---|---|---|---|---|---|
| MER | p value | MER | p value | MER | p value | |||
| p__Actinobacteria | ||||||||
| f__Actinomycetaceae | g__Actinomyces | 4.006 | .0068 | |||||
| f__Coriobacteriaceae | g__Eggerthella | 6.0133 | 0.002 | |||||
| f__Coriobacteriaceae | g__ | .2447 | .0062 | |||||
| p__Bacteroidetes | ||||||||
| f__Methanobacteriaceae | g__Methanobrevibacter | .0081 | .001 | |||||
| p__Firmicutes | ||||||||
| f__Clostridiaceae | 12.5643 | < .0001 | ||||||
| f__Clostridiaceae | g__SMB53 | 7.2232 | 0.0068 | |||||
| f__Erysipelotrichaceae | g__Catenibacterium | .0104 | .0001 | |||||
| f__Erysipelotrichaceae | g__Clostridium | 19.9947 | < .0001 | |||||
| f__Lachnospiraceae | g__Anaerostipes | .0403 | .0029 | |||||
| f__Lachnospiraceae | g__Clostridium | 8.280 | .0086 | |||||
| f__Lachnospiraceae | g__Lachnobacterium | .0143 | .0011 | |||||
| f__Streptococcaceae | g__Lactococcus | 32.8322 | < .0001 | .0419 | .0055 | |||
| f__Turicibacteraceae | g__Turicibacter | .0874 | .0028 | |||||
| f__Ruminococcaceae | .4229 | .0016 | ||||||
| f__Ruminococcaceae | g__Ruminococcus | .2068 | .0004 | |||||
| P_Proteobacteria | ||||||||
| f__Enterobacteriaceae | 10.4271 | 0.0005 | ||||||
| f__Desulfovibrionaceae | g__Bilophila | 3.0562 | .0064 | |||||
| f__Enterobacteriaceae | g__Escherichla | 31.523 | < 0.0001 | |||||
aMER > means higher taxa in women aged < 50, early menarche age (≤ 11), nulliparous, high BMI (≥ 25), high TBF(> 46%) than age 50+, later menarche (≥ 12), parous, low BMI, and low TBF, respectively
bAdjustment for total counts and race/ethnicity
cAdjustment for total counts, age and race/ethnicity in analysis on age at menarche and parity (model 2, MER)