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. 2020 Jun 10;11:1137. doi: 10.3389/fmicb.2020.01137

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Copyright © 2020 Chen, Han, Wu, Xu, Yu and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) The relative genetic diversity of E-30 sequences in China. The black arrows show the important timescale that the relative genetic diversity of E-30 decrease signally. (B) The maximum clade credibility (MCC) phylogenetic tree based on the entire VP1 coding region in China and colored according to the locations of strains. The detailed information of isolates used in this study, including GenBank accession numbers, locations, and other essential information, are presented in Supplementary Table S1. The lineages 1 and 2 show the transmission lineages of E-30 in China, corresponding to Figure 4.