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. 2020 Jun 10;11:456. doi: 10.3389/fneur.2020.00456

Table 1.

Baseline characteristics according to TyG index quartiles.

Total patients TyG index
Q1 (n = 4078) Q2 (n = 4077) Q3 (n = 4078) Q4 (n = 4077) P-value
Sex (male) (%) 10,353 (63.5) 2,810 (68.9) 2,632 (64.6) 2,544 (62.4) 2,367 (58.1) <0.0001
Age (years) 64.8 ± 11.9 67.5 ± 12.2 65.4 ± 11.8 64.0 ± 11.8 62.5 ± 11.3 <0.0001
NIHSS 4 (2–7) 4 (2–7) 4 (2–7) 4 (2–7) 4 (2–7) 0.13
IV thrombolysis (%) 890 (5.6) 218 (5.5) 229 (5.8) 215 (5.4) 228 (5.7) 0.88
SBP (mmHg) 149.2 ± 23.0 147.8 ± 23.6 148.8 ± 22.3 149.3 ± 22.3 151.0 ± 23.1 <0.0001
DBP (mmHg) 87.44 ± 13.4 85.9 ± 13.6 87.4 ± 13.4 88.0 ± 13.3 88.6 ± 13.2 <0.0001
Previous or current smoker (%) 7246 (44.4) 1921 (47.1) 1824 (44.7) 1780 (43.7) 1721 (42.2) <0.0001
Medical History
History of hypertension (%) 10593 (65.0) 2330 (57.1) 2633 (64.6) 2773 (68.0) 2857 (70.1) <0.0001
History of AF (%) 1143 (7.0) 383 (9.4) 274 (6.7) 263 (6.5) 223 (5.5) <0.0001
History of MI (%) 289 (2.4) 90 (2.2) 104 (2.6) 102 (2.5) 93 (2.9) 0.69
History of DM (%) 3408 (20.9) 277 (6.8) 501 (12.3) 855 (21.0) 1775 (43.5) <0.0001
History of previous stroke (%) 5367 (32.9) 1386 (34.0) 1354 (33.2) 1372 (33.6) 1255 (30.8) 0.0086
Pre-Hospital Mediation History
Antiplatelet drugs (%) 3191 (19.6) 786 (19.3) 822 (20.2) 769 (18.9) 814 (20.0) 0.41
Anticoagulation drugs (%) 168 (1.0) 50 (1.2) 49 (1.2) 36 (0.9) 33 (0.8) 0.14
Antihypertensive drugs (%) 7324 (44.9) 1564 (38.4) 1821 (44.7) 1924 (47.2) 2015 (49.4) <0.0001
Lipid-lowing drugs (%) 1103 (6.8) 263 (6.5) 273 (6.7) 278 (6.8) 289 (7.1) 0.71
Hypoglycemic drugs (%) 2604 (16.0) 217 (5.3) 373 (9.2) 661 (16.2) 1353 (33.2) <0.0001
Glucose Metabolism
BMI (kg/m2) 24.2 ± 3.6 23.2 ± 3.5 24.0 ± 3.4 24.6 ± 3.4 24.9 ± 3.8 <0.0001
TG (mg/dL) 119.5 (85.9−174.4) 70.0 (58.4−82.3) 106.3 (92.9−120.4) 147.9 (124.0−172.7) 228.5 (177.1−301.9) <0.0001
FBG (mg/dL) 114.1 ± 46.9 89.8 ± 16.3 98,7 ± 20.7 111.7 ± 31.1 156.2 ± 67.4 <0.0001

Data are the mean ± standard deviation, number (percentage), or median (interquartile range); TyG index, triglyceride glucose index; NIHSS, National Institutes of Health Stroke Scale; IV, intravenous; SBP, systolic blood pressure; DBP, diastolic blood pressure; AF, atrial fibrillation; MI, myocardial infarction; DM, diabetes mellitus; BMI, body mass index; TG, Triglyceride; FBG, Fasting blood glucose; Q1–Q4, TyG index quartiles; Statistically significant P values are shown in bold.