FIGURE 2.

Effect of PAF C-16 treatment on the growth of intracellular M. smegmatis. M. smegmatis infected THP-1 cell were treated for 24 h with either solvent control (10 μl ethanol/ml) or indicated concentrations of PAF C-16, before lysis and plating. The data shown as box plots represent median, interquartile and minimal and maximal values for four individual experiments performed in triplicates. The data is expressed in terms of percentage, where solvent control is considered as 100% survival. Level of significance was calculated by applying multiple comparison non-parametric Kruskal–Wallis test on ranks (p = 0.0012) and any two data sets were compared using post hoc Dunn’s multiple comparison, where PAF C-16 (1 μg/ml) vs solvent control was found to be significant, **p ≤ 0.01.