FIGURE 6.

Effect of cPLA₂ inhibitor Benzenesulfonamide on PAF C-16 induced growth inhibition of intracellular M. smegmatis. M. smegmatis infected THP-1 samples were treated for 24 h with either solvent control (10 μl ethanol/ml), Benzenesulfonamide (BS, 56 nM), PAF C-16 (1 μg/ml) or a combination of BS (56 nM) and PAF C-16 (1 μg/ml) (Test), before lysis and plating. The data is expressed in terms of percentage, where solvent control is taken as 100% survival and different treated conditions are compared to it. The data represent median, interquartile and minimal and maximal values for four individual experiments performed in triplicates. Statistically significant (*p = 0.02) difference was found for Test v 1 μg/ml PAF C-16 only treated condition using Mann–Whitney test.