TABLE 3.2.
Comparison between therapies – qualitative analysis.
| CLET | ||
| (Holoclar® + surgery) | SLET | |
| Costs to add to each surgery | ||
| Hospitalization after surgery | 1 day | Variable |
| Drugs/Medications needed | ||
| Therapeutic contact lens | Not required | Yes |
| Amniotic membrane | Not required | Yes |
| Antibiotic eye drops | + | ++ |
| Steroid eye drops | + | ++ |
| Artificial tears | + | + |
| Outpatient appointments (first year) | At least 6 appointments | At least 9 appointments |
| Other costs to add to each therapy | ||
| Home treatment | Self-medication | Medications At least 5 weeks up to complete re-epithelialization |
| Cost up to complete epithelialization | 3–7 days | 5–6 weeks |
| Invalidity/productivity loss | Days | Months |
| Pharmacovigilance on adverse event | Yes | Absent |
| Reproducibility of results | Highly standardized GMP setting | Not standardized setting |
| Proven inter-hospital consistency | Yes | No |
This Table lists different treatments included in each therapy. The list of drugs and medications was taken from Basu et al. (2016) for SLET and AIFA (2019) for Holoclar. + used during the therapy, + + used in higher amount than the comparator.