Table 1.
Maspin expression and clinicopathological features of the early stage CRC cohort.
Maspin in cytoplasm (n = 628) | Maspin in nucleus (n = 628) | |||||
---|---|---|---|---|---|---|
Low (n = 525) | High (n = 103) | p-value | Negative (n = 489) | Positive (n = 139) | p-value | |
Gender | 0.1957 | 0.2115 | ||||
Male | 274 | 46 | 256 | 64 | ||
Female | 251 | 57 | 233 | 75 | ||
Age | 0.1265 | 0.5593 | ||||
≤ 65 | 228 | 36 | 209 | 55 | ||
>65 | 297 | 67 | 280 | 84 | ||
Histology | 1.0000 | 0.1598 | ||||
Mucinous | 42 | 8 | 124 | 15 | ||
Not mucinous | 483 | 95 | 454 | 35 | ||
Tumor differentiation | 0.1665 | 0.0001 | ||||
G1/2 | 486 | 91 | 461 | 116 | ||
G3 | 39 | 12 | 28 | 23 | ||
Tumor location | 0.0526 | 0.3382 | ||||
Left | 270 | 42 | 248 | 64 | ||
Right | 255 | 61 | 241 | 75 | ||
Tumor stage | 0.1810 | 0.2331 | ||||
I | 187 | 44 | 186 | 45 | ||
II | 338 | 59 | 303 | 94 | ||
MMR status | 0.0215 | 0.0020 | ||||
MSS | 413 | 70 | 390 | 93 | ||
MSI | 112 | 33 | 99 | 46 |