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. 2020 Apr 29;45(8):1390–1397. doi: 10.1038/s41386-020-0688-x

Fig. 2. Early (baseline to week 2) Increases in VS-rostral ACC Connectivity Correlates with Week 8 Escitalopram Improvement.

Fig. 2

a Increased functional connectivity in the MDD group (n = 82) during reward anticipation from the bilateral ventral striatum to the rostral ACC (orange–yellow) significantly correlates with MADRS improvement. b Correlation of MADRS improvement with the change in VS functional connectivity during reward anticipation from baseline to week 2. Percent MADRS improvement was calculated such that a value of 100% represented a full improvement at week 8 (i.e., week 8 MADRS = 0).