Table 1.
Summary of demographic and clinical measures for HC and MDD participants.
| Healthy controls | MDD | |||
|---|---|---|---|---|
| Mean | SD | Mean | SD | |
| n Female | 29 | – | 58 | – |
| n Right-handed | 37 | – | 79 | – |
| Age | 35.31 | 12.22 | 33.61 | 11.46 |
| MADRS | ||||
| Baseline | 0.89 | 1.73 | 29.53 | 5.23 |
| Week 2 | 0.79 | 1.55 | 21.99 | 7.62 |
| Week 4 | – | – | 17.97 | 8.85 |
| Week 6 | – | – | 15.54 | 8.52 |
| Week 8 | 1.14 | 2.04 | 15.00 | 9.12 |
| Percent improvement | – | – | 49.54 | 30.05 |
| SHAPS | ||||
| Baseline | 1.36 | 2.05 | 6.93 | 3.64 |
| Week 8 | 0.72 | 1.16 | 4.06 | 3.77 |
| DARS | ||||
| Baseline | 59.65 | 9.10 | 32.98 | 13.45 |
| Week 8 | 60.21 | 7.79 | 43.53 | 16.83 |
DARS Dimensional Anhedonia Rating Scale, MADRS Montgomery-Åsberg Depression Rating Scale, MDD major depressive disorder; SD standard deviation, SHAPS Snaith–Hamilton Pleasure Scale.