Table 4.
Top 50 candidate drugs/chemicals in the CLUE database targeted to glaucoma genetic factors.
| Order | Drug | FDR < 0.05 | Order | Drug | FDR < 0.05 |
|---|---|---|---|---|---|
| 1 | Alitretinoin | 0 | 26 | MRS-1220 | 8E-08 |
| 2 | Acitretin | 0 | 27 | BFL-50481 | 8E-08 |
| 3 | Linifanib | 0 | 28 | Apoptosis-activator-Ii | 8E-08 |
| 4 | Catechin | 0 | 29 | Flavanone | 8E-08 |
| 5 | Pyrazinamide | 0 | 30 | Sa-792709 | 8E-08 |
| 6 | 10h-Phenothiazin-10-Yl)(P-tolyl)methanone | 0 | 31 | Carbenoxolone | 2.1E-07 |
| 7 | Importazole | 0 | 32 | Hydroxycholesterol | 3.49E-06 |
| 8 | Meptazinol | 0 | 33 | Deoxycholic acid | 3.49E-06 |
| 9 | Le-135 | 0 | 34 | Withaferin-A | 3.49E-06 |
| 10 | Carvedilol | 1E-08 | 35 | Valdecoxib | 3.49E-06 |
| 11 | Retinol | 3E-08 | 36 | Fostamatinib | 3.49E-06 |
| 12 | Pyridine-2-Aldoxime | 8E-08 | 37 | Rita | 3.49E-06 |
| 13 | Mestinon | 8E-08 | 38 | TTNPB | 3.49E-06 |
| 14 | Edrophonium | 8E-08 | 39 | Psb-11 | 3.49E-06 |
| 15 | Tolcapone | 8E-08 | 40 | Probucol | 3.49E-06 |
| 16 | Tamibarotene | 8E-08 | 41 | Pp-1 | 3.49E-06 |
| 17 | Tak-715 | 8E-08 | 42 | Gw-9662 | 3.49E-06 |
| 18 | BCI-Hydrochloride | 8E-08 | 43 | Eriodictyol | 3.49E-06 |
| 19 | Celastrol | 8E-08 | 44 | Umbelliferone | 3.49E-06 |
| 20 | Physostigmine | 8E-08 | 45 | Rofecoxib | 3.49E-06 |
| 21 | AZD-7762 | 8E-08 | 46 | Paxilline | 3.49E-06 |
| 22 | Tacrine | 8E-08 | 47 | PSB-1115 | 3.49E-06 |
| 23 | CAY-10470 | 8E-08 | 48 | Gw-3965 | 3.49E-06 |
| 24 | Cytarabine | 8E-08 | 49 | Flufenamic acid | 6.44E-06 |
| 25 | Ac-55649 | 8E-08 | 50 | Caffeine | 2.44E-05 |