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. 2020 May 6;45(8):1330–1338. doi: 10.1038/s41386-020-0696-x

Fig. 2. CB1 receptor antagonist rimonabant fails to prevent the anxiolytic-like effects of JZL184.

Fig. 2

The CB1-selective inverse agonist rimonabant (rim, 1 mg/kg, IP) was administered together with JZL184 (16 mg/kg, IP) and rats were tested 4 h later. a Time spent in open arms (s); b number of open arm entries; c anxiety index; d number of stretch-attend postures; e number of head dips. Results are expressed as mean ± SEM (n = 8 per group). Two-way ANOVA followed by Newman–Keuls multiple comparison test. *P < 0.05, **P < 0.01, ***P < 0.001.