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. 2020 May 6;45(8):1330–1338. doi: 10.1038/s41386-020-0696-x

Fig. 3. CB2 receptor antagonist AM630 prevents the anxiolytic-like effects of JZL184.

Fig. 3

The CB2-selective inverse agonist AM630 (5 mg/kg, IP) was administered 3 h after JZL184 (16 mg/kg, IP) and 1 h before behavioral testing. a Time spent in open arms (s); b number of open arm entries; c anxiety index; d number of stretch-attend postures; e number of head dips. Results are expressed as mean ± SEM (n = 15–16 per group). Two-way ANOVA followed by Newman–Keuls multiple comparison test. *P < 0.05, **P < 0.01, ***P < 0.001.