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. 2020 Jun 10;14:172. doi: 10.3389/fnhum.2020.00172

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Copyright © 2020 Zhao, Niu, Lei, Shah, Xiao, Zhang, Chen, Lui and Gong.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Between-group results of the brain structural connectome (corrected p < 0.05). Row 1: MDD patients compared with HCs. Row 2: SAD patients compared with HCs. Row 3: SAD patients compared with MDD patients. The purple nodes represent the regions with significantly altered morphological connections. The line width represents the t-value between groups, and the wider of the lines, the higher of the t values (for details of t values, see Table 5). Increased connections are presented in red, and decreased connections are presented in gray. Abbreviations: CAL, calcarine cortex; HCs, healthy controls; IFG triang, inferior frontal gyrus triangular part; INS, insula; ITG, inferior temporal gyrus; L, left; LING, lingual gyrus; MDD, major depressive disorder; MOG, middle occipital gyrus; PoCG, postcentral gyrus; PreCG, precentral gyrus; R, right; REC, rectus gyrus; SAD, social anxiety disorder; SMA, supplementary motor area.