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. 2020 Jun 16;11(3):e00589-20. doi: 10.1128/mBio.00589-20

FIG 8.

FIG 8

Efficient LMP1 EV secretion enhances cell proliferation and migration and tumor growth. (A) HK1 cells expressing scramble shRNA had the same cell growth and proliferation as HK1 cells expressing Syntenin-1 shRNA. HK1 cells expressing the inducible shRNAs (scramble and Syntenin-1) were plated in an xCelligence E-16 plate, and growth was monitored for about 60 h. (B and C) HK1 cells expressing inducible LMP1 accelerate cell proliferation and growth. (D and E) LMP1 EV secretion promotes cell migration. HK1 cells expressing inducible LMP1 and shRNAs (scramble and Syntenin-1) were plated in an xCelligence CIM-16 plate, and cell migration was monitored for 24 h (**, adjusted P < 0.0001). a.u, arbitrary units.