Table 1.
Antimicrobial resistance pattern, antibiotic resistance genes, virulence genes, capsular type and sequence type of isolates
| Isolate | Resistance | MIC (μg/ml) | Tn | Virulence Factor Genes | Capsular type | ST | |||
|---|---|---|---|---|---|---|---|---|---|
| Phenotype | genes | P | E | T | |||||
| 1 | CD, E, Oxa, T, TS | ermB, mefA/E, tetM | ≥256 | ≥256 | 24 | – | cbpA, cpsA, lytA | 11A | 9533 |
| 2 | Oxa, TS | tetM | 0.75 | ND | ND | – | cbpA, cpsA, lytA, ply, pspA | – | – |
| 3 | CD, E, Oxa, T, TS | ermB, tetM | 1.5 | ≥256 | 16 | – | cbpA, cpsA, lytA, ply, pspA | 19A | 15,139 |
| 4 | Oxa, TS | mefA/E | 0.094 | ND | ND | – | cbpA, cpsA, lytA, ply, pspA | – | 12,224 |
| 5 | CD, E, Oxa, T, TS | ermB, mefA/E, tetM | 48 | ≥256 | 12 | – | cbpA, cpsA, lytA | 11A | 9533 |
| 6 | CD, E, Oxa, T, TS | ermB, mefA/E, tetM | 48 | ≥256 | 16 | – | cbpA, cpsA, lytA, ply | 15B/C | – |
| 7 | CD, E, Oxa, T, TS | ermB, mefA/E, tetM | 0.19 | ≥256 | 8 | – | cbpA, cpsA, lytA, ply, pspA | 19A | – |
| 8 | CD, CLR, E, Oxa, T, TS | ermB, mefA/E, tetM | 48 | ≥256 | 16 | – | cbpA, cpsA, lytA, ply | 23F | 15,140 |
| 9 | CD, CLR, E, Oxa, T, TS | ermB, tetM | 48 | ≥256 | 16 | – | cbpA, cpsA, lytA, ply, pspA | 23F | – |
| 10 | CD, CLR, E, Oxa, T, TS | ermB, tetM | 1.5 | ≥256 | 8 | – | cbpA, cpsA, lytA, ply, pspA | 23F | – |
| 11 | Oxa, T, TS | tetM | 1 | ND | 4 | – | cbpA, cpsA, lytA, ply, pspA | 15A | |
| 12 | E, Oxa, TS | mefA/E | 0.125 | 8 | ND | – | cbpA, cpsA, lytA, ply, pspA | 14 | – |
| 13 | CD, CLR, E, Oxa, T, TS | ermB, mefA/E, tetM | 32 | ≥256 | 24 | – | cbpA, cpsA, lytA, ply, pspA | 23F | – |
| 14 | E, Oxa, TS | mefA/E | 1 | 12 | ND | – | cbpA, cpsA, lytA, ply | 6A/B | – |
| 15 | Oxa, TS | – | 0.38 | ND | ND | – | cbpA, cpsA, lytA, ply | 6A/B | – |
| 16 | CD, E, Lvo, Oxa, T, TS | ermB, tetM | 0.5 | ≥256 | 8 | – | cbpA, cpsA, lytA, ply | 19A | – |
| 17 | TS | – | 1 | ND | ND | – | cbpA, cpsA, lytA, ply | 15A | – |
| 18 | CD, CLR, E, Oxa, T, TS | ermB, tetM | 2 | ≥256 | 12 | 6002 | cbpA, cpsA, lytA, ply | 23F | – |
| 19 | E, TS, Oxa | mefA/E | 0.047 | 2 | ND | – | cbpA, cpsA, lytA, ply, pspA | 6A/B | – |
| 20 | E, CD, T, Oxa, TS | ermB, tetM | 0.5 | ≥256 | 12 | 6002 | cbpA, cpsA, lytA | 15A | – |
| 21 | E, Oxa, TS | ermB, mefA/E | 0.19 | 3 | ND | – | cbpA, cpsA, lytA | 15B/C | 1888 |
| 22 | CD, E, Oxa, T, TS | ermB, tetM | 0.5 | ≥256 | 8 | 6002 | cbpA, cpsA, lytA | 15A | – |
| 23 | Oxa, TS | tetM | 1.5 | ND | ND | – | cbpA, cpsA, lytA, pspA | 15A | – |
| 24 | E, Oxa, T, TS | mefA/E, tetM | 0.5 | 12 | 12 | 2009 | cbpA, cpsA, lytA, ply | 9 V | – |
| 25 | Oxa, T | tetM | 1.5 | ND | 8 | 916 | cbpA, cpsA, lytA, pspA | 1 | – |
| 26 | E, Oxa, T, TS, | mefA/E, tetM | 16 | 2 | 24 | 2009 | cbpA, cpsA, lytA | 19A | 1339 |
| 27 | CD, E, Oxa, T, TS | ermB, tetM | 0.38 | ≥256 | 16 | – | cbpA, cpsA, lytA, ply, pspA | 14 | – |
| 28 | Oxa, TS | – | 1 | ND | ND | – | cbpA, cpsA, lytA, ply | 6A/B | – |
| 29 | CD, CLR, E, Oxa, T, TS | ermB, tetM | 2 | ≥256 | 24 | 6002 | cbpA, cpsA, lytA, ply | 23F | – |
| 30 | CD, E, Oxa, T, TS | ermB, tetM | 1 | 24 | 16 | – | cbpA, cpsA, lytA, ply | 19F | – |
| 31 | E, Oxa, TS | mefA/E | 0.75 | 3 | ND | – | cbpA, cpsA, lytA, ply, pspA | 6A/B | – |
| 32 | CD, E, T, TS | ermB, tetM | 0.094 | 4 | 8 | 3872 | cbpA, cpsA, lytA, ply | 19A | 12,888 |
| 33 | CD, E, T, TS | ermB, tetM | 0.38 | 12 | 24 | 6002 | cbpA, cpsA, lytA, ply | 6A/B | – |
| 34 | E, Oxa, TS | mefA/E | 0.75 | 4 | ND | – | cbpA, cpsA, lytA, ply | 9 V | – |
| 35 | E, Oxa, TS | mefA/E | 0.094 | 4 | ND | – | cbpA, cpsA, lytA, ply | 6A/B | – |
| 36 | Oxa | mefA/E | 0.75 | ND | ND | – | cbpA, cpsA, lytA | 19A | – |
| 37 | Oxa, T, TS | tetM | 0.75 | ND | 8 | 916 | cbpA, cpsA, lytA, ply | – | – |
| 38 | Oxa, T, TS | ermB, tetM | 0.5 | ND | 4 | 6002 | cbpA, cpsA, lytA, ply | 15A | – |
| 39 | Oxa, T, TS | tetM | 4 | ND | 8 | 916 | cbpA, cpsA, lytA, ply | 19A | – |
| 40 | E, Oxa, T | ermB, mefA/E, tetM | 1 | 3 | 16 | 1545/6003 + MEGA | cbpA, cpsA, lytA, pspA | 11A | – |
| 41 | E, Oxa, T | ermB, mefA/E, tetM | 0.75 | 2 | 16 | 1545/6003 + MEGA | cbpA, cpsA, lytA, pspA | 11A | – |
| 42 | E, Oxa, T | mefA/E, tetM | 0.094 | 3 | 48 | 2009 | cbpA, cpsA, lytA, pspA | 15A | – |
| 43 | CD, E, Oxa, T, TS | ermB, mefA/E, tetM | 0.75 | ≥256 | 6 | 2010 | cbpA, cpsA, lytA, ply | 19F | 2533 |
| 44 | E, Oxa | mefA/E | 0.19 | 4 | ND | – | cbpA, cpsA, lytA, ply, pspA | 6A/B | 1876 |
CD clindamycin, CLR chloramphenicol, E erythromycin, Lvo levofloxacin, Oxa oxacillin, P penicillin, T tetracycline, TS trimethoprim/sulfamethoxazole, ND non-determined, Tn transposon, ST sequence type
MIC Breakpoints: Penicillin: S ≤ 2; I = 4; R ≥ 8, Tetracycline: S ≤ 1; I = 2; R ≥ 4, Erythromycin: S ≤ 0.25; I = 0.5; R ≥ 1