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. 2020 Jun 10;11:1287. doi: 10.3389/fmicb.2020.01287

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Copyright © 2020 Liang, Wagner, Li, Zhang and Radosevich.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Alpha- and beta- diversity of in vitro bacterial cell suspensions. (A) Shannon index. (B) Bacterial species richness. Data shown as the mean of triplicate cell suspensions assays, and the error bars show one standard deviation. (C) Principal component analysis (PCA) of bacterial community composition. Samples are color-coded based on AHL or mitomycin C (MIT) treatment and the control. AHL1–8 stands for induction using quorum sensing signal molecules of N-(Butyryl, Hexanoyl, β-Ketocaproyl, Heptanoyl, Octanoyl, 3-Oxododecanoyl, Tetradecanoyl, or 3-Oxotetradecanoyl) homoserine lactones, respectively. Statistical significance between the treatment and the control group is indicated by ^∗p < 0.05 and ^∗∗∗p < 0.001.