Table 1.
Timepoint | Infarction | Pre-onset of | Onset of | Reperfusion | End of experiment | p-value Time*device | |
---|---|---|---|---|---|---|---|
(T-60) | MCS (t-20) | MCS (t5) | (t40) | (t150) | (device) | ||
Parameter | Device | ||||||
art. pH | Impella | 7.40 (0.01) | 7.41 (0.05) | 7.42 (0.06) | 7.41 (0.05) | 7.45 (0.03) | 0.315 (0.621) |
ECMO | 7.41 (0.03) | 7.40 (0.06) | 7.43 (0.01) | 7.43 (0.08) | 7.43 (0.07) | ||
art. pCO2 (mmHg) | Impella | 45.50 (3.2) | 48.42 (5.8) | 44.20 (2.60) | 46.71 (4.2) | 45.42 (4.0) | 0.384 (0.569) |
ECMO | 44.50 (8.70) | 46.51 (2.10) | 43.10 (2.10) | 45.10 (3.20) | 45.10 (6.40) | ||
venous cSo2 (%) | Impella | 83.11 (7.59) | 73.30 (7.59) | 78 (2.20) | 77.11 (7.59) | 71.4 (8.09) | 0.405 (0.497) |
ECMO | 84.50 (3.19) | 71.30 (16.40) | 87.40 (14.60) | 72.80 (29.70) | 71.80 (14.20) | ||
art Lac (mmol/l) | Impella | 1.69 (0.32) | 2.59 (4.46) | 3.46 (0.91) | 2.65 (1.57) | 2.27 (0.64) | 0.414 (0.474) |
ECMO | 1.73 (0.58) | 2.88 (0.85) | 2.7 (0.90) | 2.88 (0.67) | 1.68 (1.22) | ||
CK (U/L) | Impella | 2538 (2504) | 2623 (1554) | 4533 (417) | 7626 (6922) | 20474 (5186) | 0.861 (0.415) |
ECMO | 1613 (1249) | 2080 (1512) | 3409 (770) | 4833 (2509) | 16048 (17380) | ||
Hematocrit (%) | Impella | 38.8 (6.79) | 40.3 (11.6) | 42.5 (8.20) | 40.5 (7.50) | 39.8 (8.60) | 0.018 (0.189) |
ECMO | 37.6 (5.79) | 39.8 (3.29) | 36.2 (3.29) | 36.1 (1.60) | 34.7 (2.40) | ||
Hemoglobin (g/dl) | Impella | 11.2 (2.2) | 12.5 (4.1) | 12.9 (2.4) | 11.6 (2.7) | 11.4 (3.1) | 0.008 (0.289) |
ECMO | 11.2 (1.80) | 11.9 (1.11) | 10.4 (0.69) | 10.6 (0.60) | 10.4 (0.89) | ||
Fibrinogen (g/l) | Impella | 1.39 (0.38) | 1.41 (0.22) | 1.31 (0.33) | 1.36 (0.21) | 1.31 (0.30) | 0.000 (0.719) |
ECMO | 1.47 (0.65) | 1.49 (0.70) | 1.15 (0.52) | 1.29 (0.57) | 1.21 (0.51) | ||
pfHb (mg/dl) | Impella | 6 (6) | 17 (4) | 20 (11) | 26 (15) | 18 (21) | 0.318 (0.106) |
ECMO | 8 (3) | 21 (15) | 12 (9) | 12 (7) | 8 (4) |
Data are presented as median and inter-quartile range. pfHB, plasma free hemoglobin; CK, Creatinine kinase; venous cSo2, central venous saturation; art lac, arterial Lactate.