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(A) Associations between changes of cHER2 status from baseline to first follow-up and patient progression-free survival. Longitudinal monitoring of cHER2 status using serial blood samples collected from metastatic breast cancer patients with hormonal receptor (HR) positive (B) or HR-negative (C) tumor. cHER2, human epidermal growth factor receptor 2 phenotype on circulating tumor cell; PR, partial response; PD, progressive disease.
