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. 2020 Jun 17;40(4):464–475. doi: 10.1007/s13410-020-00838-z

Table 3.

Cost profile of the reviewed studies

Ref. no. Author Publication year Cost of individual/household (without complications) Cost of individual/household (with complications)
[8] Acharya et al. 2016 The total direct cost without complication was ₹21, 258/- p.a. The total indirect cost without complication was ₹1198/- p.a.

The total direct cost with complication ₹28,888/- p.a. The total indirect cost with complication ₹1746/- p.a.

The cost of illness (COI) with complication was 1.4 times higher.

[7] Akari et al. 2013

The average total direct medical and non-medical cost was 15,588/- p.a. and

The average total indirect cost was ₹ 1079/- p.a.

The average cost with diabetic complications was ₹6633/- p.a. for macrovascular complications and ₹4798/- p.a. for microvascular complications
[51] Bjork et al. 2000 The estimated annual direct cost was ₹ 7070/individual and indirect cost was ₹12,756 including productivity and income loss through illness. ----
[43] Bjork et al. 2003 The mean total cost of diabetes in India accounts to ₹7159/- p.a. The mean direct cost of diabetes was ₹4724/-- and indirect cost, viz. hospitalisation, was 2435/- p.a. (Some regional differences in patterns of expenditure exist, with patients in the west of India likely to spend 26% more on laboratory fees, check-ups and medicines than any other region.) ----
[5] Cavanagh et al. 2012 ---- Results of the study found India to be most expensive country for a patient with a complex diabetic foot ulcer, where 68.8 months of income was required to pay for treatment. The average direct and indirect monthly cost was ₹5258 (63,096/- annually).
[41] Chandra et al. 2014

The mean annual direct cost of treatment was ₹8822/- and 52% of amount is spent on drugs and medicines.

The mean annual indirect cost of treatment was ₹3949/- of which 91.3% was wage loss.

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[9] Eshwari et al. 2018 The total cost for diabetes management was ₹5041/- p.a. of which ₹4282/- was direct cost for the treatment of diabetes and ₹462/- was spent on indirect cost.

The total cost for treatment of diabetes with comorbidities was ₹9133/- p.a.

The direct cost with complications was ₹8185/- p.a. and indirect cost amounts to be ₹508/- p.a.

[35] Grover et al. 2005 The total annual cost of care for diabetes was ₹14,508/-. The biggest proportion was made up of direct cost of ₹9865/- p.a. and remaining ₹4642/- p.a. cost burden was adding up by indirect cost. ----
[39] Joshi et al. 2013 Majority of the respondents spend ₹ 999/- p.a. on direct cost of care for diabetes. ----
[19] Kansra 2018 The mean direct cost of diabetes for consultation, lab investigation, medicines etc. was ₹9112/- monthly, whereas indirect cost for outpatient care was ₹1166/- monthly and indirect cost for inpatient care was ₹7068 per month. ----
[38] Kapur 2007 The total average yearly direct cost was observed to be ₹7158/-. However, the mean direct cost for all patients with diabetes was ₹4724/- p.a. Individuals with three or more comorbidities encountered 48% more cost of care, amounting to ₹10,593/- annually.
[50] Katam et al. 2016 The average total direct cost per patient annually was amounted to be ₹27,915/-. The highest portion of direct cost was spent on insulin and glucose test strips (40%). ----
[47] Khongrangjem et al. 2018 The total median cost of illness per month was ₹5375/-. Total cost was made up of ₹3816/- direct cost and ₹1559/- indirect cost. ----
[44] Kumar et al. 2008 The total mean evaluation of annual direct spending on ambulatory diabetes care was ₹6000/-. ----
[49] Kumar and Mukherjee 2014 The total direct expenditure incurred on diabetes was ₹76,779/- p.a. and total indirect expenditure was ₹30,670/- p.a. ----
[2] Kumpatla et al. 2013 The total direct cost estimates without any complication were observed to be ₹4493/-. The total cost of expenditure with complication was ₹15,280/-. (cost for patients with foot complication was ₹19,020/-, also average cost for renal patients was ₹12,690/- followed by 13,135/- for cardiovascular disease.)
[36] Ramachandran 2007 The average inpatient and outpatient cost of diabetes is ₹7505/- p.a. and ₹3310/- p.a. ----
[34] Ramachandran et al. 2007 The total median direct expenditure on health care was ₹8130/- p.a. ----
[23] Rao et al. 2011 The mean cost per hospitalizations was ₹5925/- p.a. for diabetes. ----
[33] Rayappa et al. 1999 The direct annual cost (incl. hospital, test, monitoring etc.) was ₹15,460/- and indirect annual cost was ₹3572/-. ----
[42] Sachidanandaa et al. 2010 The annual medical cost spent on diabetes was ₹10,584.7/-. The annual medicine (direct) cost spent by complicated non-hospitalised was ₹19,326.91/- and ₹25,960.2/- by complicated hospitalised patients
[53] Satyavani et al. 2014 ---- Monthly diabetic patients with chronic kidney disease spend ₹12,664/- on treatment.
[37] Sharma et al. 2016 The direct annual cost was maximum for private clinics ₹19,552/- and Indirect cost was ₹2462/-. ----
[6] Shivaprakash et al. 2012 The average cost per visit (direct cost) was ₹377/- in 2010 in comparison to ₹363/- in 2005. The average cost per visit (direct cost) for patients with complications was ₹464/- in 2010.
[40] Shobhana et al. 2000 The total direct cost (incl. drugs, tests, consultation, hospital, surgery, transport) was ₹4510/- half yearly.
[45] Shobhana et al. 2002 ₹13,980/- was spent annually on direct costs of diabetes by the patients. ----
[48] Singla et al. 2019 The total direct cost (drugs and medicine) for diabetes patients was ₹3241 p.m. ----
[46] Thakur et al. 2017 The mean annual direct expenditure for diabetes care was ₹9832 and indirect cost was ₹5622. ----
[52] Tharkar et al. 2009 The total direct cost for hospitalisation was ₹14,000 p.a. The total direct cost for hospitalisation with comorbidities was ₹19,000/- p.a.
[22] Tharkar et al. 2010 The median annual direct cost associated with diabetes care was ₹25,391 and indirect cost was ₹4970, respectively. ----
[24] Tripathy and Prasad 2018 The annual median out-of-pocket household expenditure because of hospitalisation due to diabetes was ₹9996.20/-. ----
[20] Viswanathan and Rao 2013 The annual direct and indirect cost to treat diabetes was ₹16,756 and ₹5504/- ----

Source: Authors’ compilation established on reviewed articles