Table 3.
Age-standardized death ratesa and fixed-interval trends (2013–2017)b for the most common causes of cancer death,c by sex and racial/ethnic group,d United Statese
| Sex/cancer site or type | All Races | Non-Hispanic White | Non-Hispanic Black | Non-Hispanic API | Non-Hispanic AI/AN (PRCDA) | Hispanic | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Rank | Rate (95% CI) | AAPC (95% CI) | P | Rate (95% CI) | AAPC (95% CI) | P | Rate (95% CI) | AAPC (95% CI) | P | Rate (95% CI) | AAPC (95% CI) | P | Rate (95% CI) | AAPC (95% CI) | Rate (95% CI) | AAPC (95% CI) | P | ||||||||
| All sites | |||||||||||||||||||||||||
| Both sexes | 158.2 (158.0, 158.3) | −1.5 (−1.6, −1.5) | f | <.001 | 162.9 (162.7, 163.1) | −1.4 (−1.4, −1.3) | f | <.001 | 186.4 (185.8, 187.1) | −2.0 (−2.1, −2.0) | f | <.001 | 98.9 (98.3, 99.6) | −1.3 (−1.4, −1.2) | f | <.001 | 166.0 (162.8, 169.3) | −0.6 (−0.9, −0.3) | f | <.001 | 111.8 (111.3, 112.3) | −1.3 (−1.4, −1.2) | f | <.001 | |
| Males | 189.3 (189.0, 189.6) | −1.8 (−1.9, −1.8) | f | <.001 | 193.8 (193.4, 194.1) | −1.6 (−1.7, −1.6) | f | <.001 | 233.2 (232.1, 234.4) | −2.6 (−2.7, −2.6) | f | <.001 | 117.4 (116.2, 118.5) | −1.6 (−1.8, −1.5) | f | <.001 | 200.3 (194.8, 205.8) | −0.5 (−1.0, 0.0) | f | .03 | 135.6 (134.7, 136.5) | −1.6 (−1.7, −1.6) | f | <.001 | |
| Females | 135.5 (135.3, 135.7) | −1.4 (−1.4, −1.4) | f | <.001 | 139.9 (139.6, 140.2) | −1.3 (−1.3, −1.3) | f | <.001 | 157.5 (156.8, 158.3) | −1.6 (−1.6, −1.5) | f | <.001 | 85.7 (84.8, 86.5) | −1.0 (−1.2, −0.9) | f | <.001 | 141.0 (137.1, 144.9) | −0.9 (−1.1, −0.6) | f | <.001 | 95.1 (94.4, 95.7) | −1.0 (−1.1, −0.9) | f | <.001 | |
| Children (ages 0–14 years) | 2.1 (2.0, 2.1) | −1.4 (−1.8, −1.1) | f | <.001 | 2.1 (2.0, 2.2) | −1.4 (−1.8, −1.1) | f | <.001 | 2.1 (2.0, 2.3) | −1.2 (−1.9, −0.6) | f | <.001 | 1.8 (1.6, 2.0) | −1.6 (−3.3, 0.2) | .07 | 2.6 (2.0, 3.4) | —g | 2.1 (2.0, 2.2) | −1.6 (−2.2, −1.1) | f | <.001 | ||||
| AYA (ages 15–39 years) | 8.9 (8.9, 9.0) | −1.0 (−1.2, −0.7) | f | <.001 | 8.9 (8.8, 9.0) | −1.2 (−1.5, −0.9) | f | <.001 | 11.4 (11.2, 11.7) | −1.6 (−1.8, −1.3) | f | <.001 | 6.9 (6.7, 7.2) | −0.8 (−1.3, −0.4) | f | .002 | 11.0 (9.8, 12.4) | −0.5 (−2.2, 1.1) | .50 | 8.1 (7.9, 8.2) | 1.1 (0.6, 1.6) | f | .001 | ||
| Males | |||||||||||||||||||||||||
| Lung and Bronchus | 1 | 49.3 (49.1, 49.4) | −4.8 (−5.4, −4.2) | f | <.001 | 51.8 (51.7, 52.0) | −4.4 (−4.7, −4.1) | f | <.001 | 60.4 (59.8, 61.0) | −5.7 (−6.3, −5.2) | f | <.001 | 29.3 (28.7, 29.9) | −3.0 (−3.4, −2.5) | f | <.001 | 46.5 (43.9, 49.2) | −1.5 (−2.4, −0.7) | f | .002 | 24.1 (23.7, 24.5) | −5.4 (−8.0, −2.6) | f | <.001 |
| Prostate | 2 | 19.1 (19.0, 19.2) | −0.3 (−1.6, 1.0) | .60 | 18.0 (17.9, 18.1) | 0.1 (−1.2, 1.4) | .88 | 38.7 (38.2, 39.2) | −3.9 (−4.2, −3.6) | f | <.001 | 8.6 (8.3, 9.0) | −2.3 (−2.8, −1.8) | f | <.001 | 21.2 (19.3, 23.3) | −1.2 (−2.4, −0.1) | f | .04 | 15.7 (15.4, 16.0) | −0.7 (−2.2, 0.7) | .32 | |||
| Colon and Rectum | 3 | 16.6 (16.5, 16.7) | −2.3 (−2.5, −2.1) | f | <.001 | 16.3 (16.2, 16.4) | −1.8 (−2.3, −1.2) | f | <.001 | 23.8 (23.5, 24.2) | −2.6 (−2.8, −2.4) | f | <.001 | 11.5 (11.1, 11.9) | −2.1 (−2.5, −1.7) | f | <.001 | 23.1 (21.3, 25.0) | 0.2 (−1.0, 1.4) | .77 | 14.1 (13.9, 14.4) | −1.7 (−1.9, −1.5) | f | <.001 | |
| Pancreas | 4 | 12.7 (12.6, 12.7) | 0.3 (0.2, 0.4) | f | <.001 | 13 (12.9, 13.1) | 0.5 (0.4, 0.6) | f | <.001 | 15.3 (15.0, 15.6) | −0.2 (−0.4, 0.0) | .06 | 8.2 (7.9, 8.5) | 0.0 (−0.5, 0.4) | .98 | 11.9 (10.6, 13.3) | 0.0 (−1.6, 1.7) | .95 | 9.3 (9.1, 9.5) | −0.1 (−0.5, 0.4) | .69 | ||||
| Liver and Intrahepatic Bile Duct | 5 | 9.6 (9.6, 9.7) | 0.5 (−0.5, 1.5) | .28 | 8.4 (8.3, 8.4) | 1.0 (0.4, 1.6) | f | .004 | 13.5 (13.3, 13.8) | −0.3 (−1.4, 0.9) | .65 | 13.5 (13.1, 13.9) | −3.7 (−4.9, −2.4) | f | <.001 | 17 (15.5, 18.5) | 2.8 (1.7, 4.0) | f | <.001 | 13.2 (12.9, 13.5) | 1.2 (0.9, 1.6) | f | <.001 | ||
| Leukemia | 6 | 8.6 (8.5, 8.6) | −2.7 (−3.5, −2.0) | f | <.001 | 9.1 (9.0, 9.2) | −2.2 (−2.8, −1.6) | f | <.001 | 7.2 (7.0, 7.4) | −1.8 (−2.2, −1.3) | f | <.001 | 4.8 (4.5, 5.0) | −0.6 (−1.4, 0.3) | .17 | 6.0 (5.1, 7.0) | −0.5 (−2.4, 1.4) | .56 | 5.8 (5.6, 6.0) | −1.0 (−1.5, −0.5) | f | .001 | ||
| Urinary Bladder | 7 | 7.5 (7.4, 7.6) | −1.1 (−2.0, −0.2) | f | .02 | 8.3 (8.2, 8.4) | −0.8 (−1.9, 0.2) | .11 | 5.5 (5.3, 5.6) | −0.3 (−0.8, 0.2) | .27 | 2.8 (2.7, 3.0) | −0.4 (−1.3, 0.6) | .43 | 4.6 (3.8, 5.6) | —g | 3.9 (3.7, 4.1) | −0.7 (−1.4, 0.0) | .06 | ||||||
| Non-Hodgkin Lymphoma | 8 | 7.1 (7.1, 7.2) | −2.0 (−2.1, −1.8) | f | <.001 | 7.5 (7.4, 7.6) | −1.9 (−2.2, −1.7) | f | <.001 | 5.3 (5.1, 5.5) | −1.8 (−2.3, −1.2) | f | <.001 | 4.9 (4.7, 5.2) | −1.4 (−1.9, −0.8) | f | <.001 | 6.3 (5.3, 7.3) | 0.2 (−1.7, 2.1) | .84 | 5.9 (5.7, 6.1) | −1.4 (−1.8, −1.0) | f | <.001 | |
| Esophagus | 9 | 7.0 (6.9, 7.1) | −1.2 (−1.4, −1.0) | f | <.001 | 7.8 (7.8, 7.9) | −0.5 (−0.7, −0.3) | f | <.001 | 5.5 (5.3, 5.6) | −4.8 (−5.2, −4.5) | f | <.001 | 2.8 (2.6, 3.0) | −1.4 (−2.3, −0.5) | f | .006 | 7.1 (6.1, 8.2) | −0.7 (−2.6, 1.2) | .42 | 3.6 (3.5, 3.8) | −1.4 (−2.1, −0.6) | f | .001 | |
| Kidney and Renal Pelvis | 10 | 5.4 (5.4, 5.5) | −2.4 (−3.0, −1.8) | f | <.001 | 5.6 (5.5, 5.7) | −2.3 (−4.2, −0.5) | f | .02 | 5.6 (5.4, 5.8) | −0.9 (−1.3, −0.5) | f | <.001 | 2.6 (2.4, 2.8) | −0.1 (−1.3, 1.1) | .85 | 9.7 (8.5, 10.9) | −0.7 (−2.1, 0.7) | .28 | 5.0 (4.8, 5.1) | −0.8 (−1.4, −0.3) | f | .007 | ||
| Brain and Other Nervous System | 11 | 5.4 (5.3, 5.4) | 0.4 (0.1, 0.8) | f | .01 | 6.1 (6.1, 6.2) | 0.7 (0.4, 1.0) | f | <.001 | 3.3 (3.2, 3.4) | 0.3 (−0.4, 0.9) | .40 | 2.6 (2.5, 2.8) | 0.3 (−0.6, 1.2) | .48 | 3.2 (2.6, 4.0) | 0.7 (−1.7, 3.2) | .53 | 3.5 (3.4, 3.6) | 0.4 (−0.1, 0.9) | .13 | ||||
| Myeloma | 12 | 4.1 (4.1, 4.2) | −0.9 (−1.1, −0.7) | f | <.001 | 3.9 (3.9, 4.0) | −0.9 (−1.1, −0.6) | f | <.001 | 7.7 (7.4, 7.9) | −0.9 (−1.2, −0.6) | f | <.001 | 2.0 (1.9, 2.2) | 0.1 (−0.9, 1.1) | .81 | 4.1 (3.3, 5.0) | −1.6 (−3.3, 0.1) | .06 | 3.4 (3.2, 3.5) | −0.4 (−1.1, 0.3) | .28 | |||
| Stomach | 13 | 4.1 (4.1, 4.1) | −2.5 (−2.7, −2.2) | f | <.001 | 3.2 (3.1, 3.2) | −2.7 (−3.1, −2.2) | f | <.001 | 8.0 (7.8, 8.3) | −3.1 (−3.4, −2.8) | f | <.001 | 6.7 (6.4, 7.0) | −3.6 (−4.0, −3.1) | f | <.001 | 7.6 (6.5, 8.7) | −2.9 (−4.8, −1.0) | f | .005 | 6.4 (6.2, 6.6) | −2.8 (−3.2, −2.4) | f | <.001 |
| Oral Cavity and Pharynx | 14 | 3.9 (3.9, 4.0) | 1.0 (0.5, 1.5) | f | .002 | 4.0 (4.0, 4.1) | 1.4 (0.9, 1.9) | f | <.001 | 4.6 (4.5, 4.8) | −2.9 (−3.5, −2.2) | f | <.001 | 3.1 (3.0, 3.3) | 1.3 (−0.3, 2.9) | .10 | 4.0 (3.3, 4.8) | 0.0 (−2.4, 2.4) | .98 | 2.4 (2.3, 2.5) | 1.2 (−0.7, 3.0) | .20 | |||
| Melanoma of the Skin | 15 | 3.5 (3.5, 3.6) | −6.1 (−7.6, −4.5) | f | <.001 | 4.5 (4.4, 4.5) | −5.7 (−7.2, −4.1) | f | <.001 | 0.4 (0.4, 0.5) | −1.4 (−3.4, 0.6) | .15 | 0.4 (0.3, 0.4) | —g | 1.2 (0.8, 1.7) | —g | 0.9 (0.8, 1.0) | −3.4 (−5.7, −1.1) | f | .009 | |||||
| Non-Melanoma | 16 | 1.7 (1.7, 1.8) | 0.7 (−3.1, 4.6) | .73 | 2.0 (2.0, 2.0) | 1.5 (−2.3, 5.4) | .44 | 0.7 (0.6, 0.8) | −2.7 (−3.8, −1.6) | f | <.001 | 0.4 (0.3, 0.5) | —g | 1.0 (0.7, 1.5) | —g | 0.8 (0.7, 0.9) | 0.6 (−0.7, 2.0) | .34 | |||||||
| Larynx | 17 | 1.7 (1.7, 1.8) | −2.5 (−2.7, −2.3) | f | <.001 | 1.7 (1.6, 1.7) | −2.1 (−2.3, −1.9) | f | <.001 | 3.1 (3.0, 3.3) | −3.6 (−4.0, −3.2) | f | <.001 | 0.6 (0.5, 0.7) | −2.9 (−4.8, −0.9) | f | .007 | 1.9 (1.4, 2.5) | —g | 1.4 (1.3, 1.5) | −4.4 (−6.5, −2.3) | f | .002 | ||
| Soft Tissue including Heart | 18 | 1.5 (1.5, 1.6) | 0.5 (0.3, 0.8) | f | .001 | 1.6 (1.6, 1.6) | 0.6 (0.2, 0.9) | f | .002 | 1.6 (1.5, 1.7) | 0.5 (−0.4, 1.4) | .24 | 1.0 (0.9, 1.1) | 0.5 (−1.4, 2.4) | .58 | 1.7 (1.2, 2.2) | —g | 1.2 (1.1, 1.3) | 1.1 (0.0, 2.1) | f | .04 | ||||
| Bones and Joints | 19 | 0.6 (0.5, 0.6) | 0.4 (−0.1, 0.8) | .08 | 0.6 (0.6, 0.6) | 0.4 (−0.1, 0.9) | .13 | 0.6 (0.5, 0.7) | 0.5 (−0.5, 1.5) | .29 | 0.3 (0.3, 0.4) | 2.4 (0.2, 4.8) | f | .04 | 0.7 (0.4, 1.0) | —g | 0.5 (0.4, 0.5) | 0.0 (−1.5, 1.6) | .97 | ||||||
| Females | |||||||||||||||||||||||||
| Lung and Bronchus | 1 | 33.2 (33.1, 33.3) | −3.7 (−4.3, −3.1) | f | <.001 | 36.8 (36.7, 36.9) | −3.3 (−3.9, −2.7) | f | <.001 | 31.9 (31.6, 32.3) | −4.6 (−5.7, −3.4) | f | <.001 | 16.9 (16.6, 17.3) | −3.7 (−5.9, −1.4) | f | .002 | 32.6 (30.7, 34.5) | −2.2 (−3.2, −1.3) | f | <.001 | 12.6 (12.4, 12.9) | −3.7 (−6.5, −0.9) | f | .01 |
| Breast | 2 | 20.3 (20.2, 20.4) | −1.2 (−1.4, −1.0) | f | <.001 | 20.3 (20.2, 20.4) | −1.1 (−1.4, −0.8) | f | <.001 | 28.4 (28.1, 28.8) | −1.5 (−1.6, −1.4) | f | <.001 | 11.5 (11.2, 11.8) | −0.7 (−1.2, −0.3) | f | .003 | 16.6 (15.2, 17.9) | 3.9 (−2.8, 11.0) | .23 | 14.0 (13.7, 14.2) | −1.1 (−1.4, −0.9) | f | <.001 | |
| Colon and Rectum | 3 | 11.7 (11.7, 11.8) | −1.6 (−2.3, −0.8) | f | .001 | 11.7 (11.7, 11.8) | −1.6 (−2.1, −1.1) | f | <.001 | 15.6 (15.4, 15.9) | −3.1 (−3.3, −2.9) | f | <.001 | 8.1 (7.9, 8.4) | −2.0 (−2.6, −1.5) | f | <.001 | 15 (13.7, 16.3) | −0.6 (−2.0, 0.7) | .34 | 8.7 (8.5, 8.9) | −2.1 (−2.4, −1.9) | f | <.001 | |
| Pancreas | 4 | 9.6 (9.5, 9.6) | 0.2 (0.1, 0.3) | f | .001 | 9.6 (9.5, 9.6) | 0.3 (0.2, 0.5) | f | <.001 | 12.3 (12.1, 12.5) | −0.2 (−0.4, 0.0) | f | .03 | 7.1 (6.8, 7.3) | 0.1 (−0.3, 0.5) | .71 | 8.9 (7.9, 9.9) | 0.3 (−1.4, 2.0) | .70 | 7.8 (7.6, 7.9) | 0.0 (−0.2, 0.3) | .95 | |||
| Ovary | 5 | 6.9 (6.8, 6.9) | −2.3 (−2.5, −2.2) | f | <.001 | 7.3 (7.2, 7.4) | −2.4 (−2.6, −2.2) | f | <.001 | 6.1 (6.0, 6.3) | −1.6 (−2.0, −1.3) | f | <.001 | 4.5 (4.3, 4.6) | −0.9 (−1.4, −0.4) | f | .002 | 7.1 (6.3, 8.0) | −1.1 (−2.3, 0.2) | .10 | 5.1 (5.0, 5.3) | −1.5 (−1.8, −1.1) | f | <.001 | |
| Corpus and Uterus, NOS | 6 | 4.8 (4.8, 4.9) | 2.1 (1.7, 2.4) | f | <.001 | 4.5 (4.4, 4.5) | 1.9 (1.5, 2.4) | f | <.001 | 8.8 (8.6, 9.0) | 2.3 (1.8, 2.9) | f | <.001 | 3.2 (3.0, 3.3) | 2.6 (1.9, 3.4) | f | <.001 | 4.0 (3.4, 4.7) | —g | 4.0 (3.9, 4.1) | 2.6 (2.0, 3.3) | f | <.001 | ||
| Leukemia | 7 | 4.8 (4.8, 4.8) | −1.3 (−1.5, −1.2) | f | <.001 | 5.0 (5.0, 5.1) | −1.2 (−1.4, −1.1) | f | <.001 | 4.4 (4.3, 4.6) | −1.5 (−1.8, −1.1) | f | <.001 | 2.6 (2.5, 2.8) | −4.6 (−7.4, −1.6) | f | .006 | 3.5 (2.9, 4.1) | −2.1 (−4.4, 0.3) | .08 | 3.7 (3.6, 3.9) | −0.8 (−1.2, −0.3) | f | .002 | |
| Non-Hodgkin Lymphoma | 8 | 4.2 (4.2, 4.3) | −2.6 (−2.8, −2.5) | f | <.001 | 4.5 (4.4, 4.5) | −2.2 (−2.8, −1.6) | f | <.001 | 3.3 (3.2, 3.4) | −2.2 (−2.5, −1.8) | f | <.001 | 3.0 (2.8, 3.1) | −2.1 (−2.7, −1.4) | f | <.001 | 3.7 (3.1, 4.4) | −3.4 (−5.3, −1.5) | f | .002 | 3.7 (3.6, 3.8) | −2.0 (−2.6, −1.5) | f | <.001 |
| Liver and Intrahepatic Bile Duct | 9 | 4.0 (3.9, 4.0) | 1.6 (1.0, 2.2) | f | .001 | 3.5 (3.5, 3.5) | 2.2 (2.0, 2.4) | f | <.001 | 4.9 (4.7, 5.0) | 1.8 (1.3, 2.3) | f | <.001 | 5.6 (5.4, 5.8) | −1.3 (−2.1, −0.6) | f | .001 | 8.1 (7.2, 9.1) | 1.0 (−1.1, 3.1) | .32 | 6.0 (5.8, 6.1) | 1.2 (0.8, 1.5) | f | <.001 | |
| Brain and Other Nervous System | 10 | 3.6 (3.6, 3.6) | 0.5 (0.2, 0.8) | f | .003 | 4.1 (4.1, 4.2) | 0.7 (0.3, 1.1) | f | .002 | 2.2 (2.1, 2.3) | 0.4 (−0.3, 1.1) | .21 | 1.9 (1.8, 2.1) | 2.1 (1.0, 3.2) | f | .001 | 2.7 (2.2, 3.3) | —g | 2.6 (2.5, 2.7) | 0.6 (0.1, 1.1) | f | .02 | |||
| Myeloma | 11 | 2.6 (2.6, 2.6) | −1.9 (−3.0, −0.9) | f | .003 | 2.3 (2.3, 2.4) | −1.7 (−2.7, −0.7) | f | .004 | 5.4 (5.3, 5.6) | −1.0 (−1.6, −0.5) | f | .001 | 1.2 (1.1, 1.3) | −1.2 (−2.7, 0.3) | .10 | 3.3 (2.7, 4.0) | −1.1 (−3.9, 1.7) | .41 | 2.2 (2.1, 2.3) | −1.4 (−2.0, −0.8) | f | <.001 | ||
| Kidney and Renal Pelvis | 12 | 2.3 (2.3, 2.3) | −1.4 (−1.6, −1.3) | f | <.001 | 2.4 (2.3, 2.4) | −1.4 (−1.6, −1.2) | f | <.001 | 2.3 (2.2, 2.4) | −1.6 (−2.0, −1.1) | f | <.001 | 1.1 (1.0, 1.2) | −1.0 (−2.1, 0.1) | .06 | 4.0 (3.3, 4.7) | −1.6 (−3.5, 0.3) | .09 | 2.2 (2.1, 2.3) | −0.7 (−1.2, −0.1) | f | .03 | ||
| Cervix Uteri | 13 | 2.3 (2.2, 2.3) | −0.7 (−0.9, −0.4) | f | <.001 | 2.1 (2.0, 2.1) | −0.1 (−0.4, 0.2) | .43 | 3.6 (3.4, 3.7) | −2.4 (−2.8, −2.1) | f | <.001 | 1.7 (1.6, 1.9) | −2.2 (−3.2, −1.1) | f | <.001 | 3.1 (2.6, 3.7) | −1.7 (−3.6, 0.2) | .08 | 2.6 (2.5, 2.7) | −0.2 (−1.8, 1.4) | .75 | |||
| Stomach | 14 | 2.2 (2.2, 2.2) | −1.8 (−2.2, −1.4) | f | <.001 | 1.6 (1.6, 1.6) | −3.0 (−3.2, −2.7) | f | <.001 | 3.7 (3.6, 3.8) | −3.4 (−3.8, −3.1) | f | <.001 | 4.1 (3.9, 4.3) | −3.1 (−3.6, −2.5) | f | <.001 | 4.1 (3.4, 4.8) | −2.9 (−4.7, −1.1) | f | .005 | 4.0 (3.8, 4.1) | −1.9 (−2.4, −1.4) | f | <.001 |
| Urinary Bladder | 15 | 2.1 (2.1, 2.2) | −0.5 (−0.7, −0.4) | f | <.001 | 2.3 (2.2, 2.3) | −0.2 (−0.4, 0.0) | f | .02 | 2.4 (2.3, 2.5) | −1.4 (−1.9, −1.0) | f | <.001 | 0.9 (0.8, 1.0) | −1.0 (−2.1, 0.0) | .06 | 1.9 (1.4, 2.4) | —g | 1.3 (1.2, 1.3) | −0.7 (−1.6, 0.1) | .08 | ||||
| Melanoma of the Skin | 16 | 1.5 (1.4, 1.5) | −6.3 (−8.6, −3.8) | f | <.001 | 1.9 (1.9, 1.9) | −5.9 (−8.5, −3.2) | f | .001 | 0.3 (0.3, 0.3) | −2.2 (−3.7, −0.7) | f | .009 | 0.3 (0.2, 0.3) | −0.4 (−3.3, 2.6) | .77 | 0.5 (0.3, 0.8) | —g | 0.5 (0.5, 0.6) | −1.6 (−2.9, −0.4) | f | .02 | |||
| Esophagus | 17 | 1.4 (1.4, 1.5) | −1.6 (−1.8, −1.4) | f | <.001 | 1.5 (1.5, 1.5) | −0.9 (−1.1, −0.7) | f | <.001 | 1.7 (1.6, 1.8) | −4.3 (−4.8, −3.8) | f | <.001 | 0.6 (0.6, 0.7) | −2.3 (−3.9, −0.7) | f | .008 | 1.4 (1.1, 1.9) | —g | 0.7 (0.7, 0.8) | −2.2 (−3.0, −1.4) | f | <.001 | ||
| Oral Cavity and Pharynx | 18 | 1.3 (1.3, 1.4) | 1.4 (−1.4, 4.3) | .31 | 1.4 (1.4, 1.4) | 2.0 (−0.5, 4.6) | .10 | 1.3 (1.3, 1.4) | −2.1 (−2.8, −1.4) | f | <.001 | 1.1 (1.0, 1.2) | −1.5 (−2.9, −0.2) | f | .03 | 1.2 (0.9, 1.6) | —g | 0.8 (0.7, 0.9) | −0.2 (−1.2, 0.8) | .71 | |||||
| Soft Tissue including Heart | 19 | 1.2 (1.1, 1.2) | 0.2 (0.0, 0.3) | f | .02 | 1.2 (1.1, 1.2) | 0.1 (−0.1, 0.3) | .45 | 1.5 (1.4, 1.6) | 0.8 (0.5, 1.2) | f | <.001 | 0.8 (0.7, 0.9) | 0.8 (−0.7, 2.4) | .26 | 1.1 (0.8, 1.5) | —g | 0.9 (0.9, 1.0) | 0.6 (−0.5, 1.6) | .27 | |||||
| Gallbladder | 20 | 0.7 (0.7, 0.7) | −1.2 (−1.5, −0.8) | f | <.001 | 0.6 (0.6, 0.6) | −1.7 (−2.1, −1.4) | f | <.001 | 1.0 (1.0, 1.1) | 0.0 (−0.8, 0.8) | .94 | 0.8 (0.7, 0.8) | −0.9 (−2.1, 0.4) | .17 | 1.8 (1.4, 2.3) | −2.6 (−4.6, −0.5) | f | .02 | 1.1 (1.1, 1.2) | −1.6 (−2.5, −0.6) | f | .003 | ||
| Children | |||||||||||||||||||||||||
| Brain and other nervous system | 0.7 (0.7, 0.7) | −0.2 (−0.7, 0.2) | .27 | 0.7 (0.7, 0.8) | −0.4 (−1.0, 0.2) | .17 | 0.7 (0.7, 0.8) | 0.5 (−0.9, 1.9) | .48 | 0.5 (0.4, 0.7) | −0.9 (−3.2, 1.4) | .41 | 0.9 (0.6, 1.4) | —g | 0.7 (0.6, 0.7) | 0.2 (−0.6, 0.9) | .66 | ||||||||
| Leukemia | 0.5 (0.5, 0.6) | −2.8 (−3.5, −2.2) | f | <.001 | 0.5 (0.5, 0.5) | −3 (−3.8, −2.3) | f | <.001 | 0.5 (0.4, 0.6) | −2.4 (−3.7, −1.2) | f | .001 | 0.5 (0.4, 0.6) | −3.7 (−5.6, −1.7) | f | .001 | 0.8 (0.5, 1.2) | —g | 0.7 (0.6, 0.7) | −3.3 (−4.4, −2.2) | f | <.001 | |||
| AYA | |||||||||||||||||||||||||
| Female Breast | 2.2 (2.1, 2.3) | 0.6 (−0.8, 2.1) | .36 | 2.0 (2.0, 2.1) | 0.9 (−1.3, 3.0) | .40 | 3.9 (3.7, 4.2) | −2.3 (−2.7, −2.0) | f | <.001 | 1.3 (1.1, 1.5) | −0.7 (−2.7, 1.4) | .49 | 1.6 (1.0, 2.4) | —g | 1.8 (1.7, 1.9) | −0.8 (−2.1, 0.5) | .22 | |||||||
| Brain and other nervous system | 1.0 (0.9, 1.0) | −0.2 (−0.7, 0.3) | .36 | 1.2 (1.2, 1.2) | −0.1 (−0.6, 0.5) | .78 | 0.6 (0.6, 0.7) | 0.4 (−0.8, 1.6) | .51 | 0.6 (0.6, 0.7) | 1.4 (−0.5, 3.3) | .14 | 0.8 (0.5, 1.2) | —g | 0.6 (0.6, 0.7) | 0.8 (−0.2, 1.8) | .12 | ||||||||
| Leukemia | 0.9 (0.9, 1.0) | −2.2 (−2.6, −1.8) | f | <.001 | 0.8 (0.8, 0.8) | −2.9 (−3.5, −2.4) | f | <.001 | 1.0 (0.9, 1.1) | −2.4 (−3.2, −1.5) | f | <.001 | 0.8 (0.7, 0.9) | −1.2 (−2.6, 0.3) | .10 | 1.1 (0.8, 1.5) | —g | 1.3 (1.2, 1.3) | −1.1 (−1.7, −0.5) | f | .002 | ||||
| Colon and rectum | 0.9 (0.8, 0.9) | 0.9 (0.5, 1.3) | f | <.001 | 0.9 (0.9, 0.9) | 1.5 (0.8, 2.2) | f | <.001 | 1.2 (1.1, 1.3) | 0.7 (−0.2, 1.5) | .11 | 0.7 (0.6, 0.8) | −0.3 (−2.2, 1.7) | .78 | 1.4 (1.0, 1.9) | —g | 0.6 (0.6, 0.7) | 1.3 (0.3, 2.3) | f | .01 | |||||
Abbreviations: AAPC, average annual percent change; AI/AN, American Indian/Alaska Native; API, Asian/Pacific Islander; AYA, adolescents and young adults; CI, confidence interval; NOS, not otherwise specified; PRCDA, Indian Health Service Purchased/Referred Care Delivery Area.
a
Rates are per 100,000 persons and age standardized to the 2000 US standard population (19 age groups - Census P25–1130).
b
Fixed interval trends are characterized as the average annual percent change (AAPC), the weighted average of the annual percent changes over the fixed interval 2013–2017, using the underlying Joinpoint model (with up to three joinpoints) for the period of 2001–2017. Joinpoint Regression Program, Version 4.7.0.0 February 2019, Statistical Research and Applications Branch,
c
Cancers are listed in descending rank order of sex-specific, age-adjusted death rates for 2013–2017 for all racial/ethnic groups combined. More than 15 cancers may appear males and females to include the top 15 cancers in each racial/ethnic group.
d
Racial/ethnic groups are mutually exclusive. Data for non-Hispanic AI/AN are restricted to PRCDA counties.
e
Based on data from the National Center for Health Statistics public-use data file for the total United States, 2001–2017.
f
The AAPC is statistically significantly different from zero (P < .05). Two-sided statistical significance for AAPC was determined using a t-test when the AAPC lay entirely within the last joinpoint segment or a z-test when the AAPC extended beyond the last joinpoint segment.
g
The statistic could not be calculated. The average annual percent change is based on <10 cases for at least 1 year within the time interval.