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. 2020 May 6;21(8):541–547. doi: 10.2217/pgs-2019-0195

Table 3. . Distribution of HLA-DRB1*07:01 and DQB1*02:02 alleles in childhood acute lymphoblastic leukemia patients in the replication cohort with and without systemic allergies.

HLA allele Genotype Allergies OR (95% CI) p-value
    Presence N (%) Absence N (%)    
DRB1*07:01 0 21 (60.0) 155 (74.5) 1  
DRB1*07:01- (DQB1*02:02)+ 1 12 (34.3) 38 (18.3) 2.3 (1.1–5.2) 0.003
DRB1*07:01- (DQB1*02:02)- 1 2 (5.7) 15 (7.2) 1.0 (0.2–4.6) 1.0

%: Frequency.

The association analysis in patients treated with Escherichia coli ASNase for DRB1*07:01 allele accompanied (+) or not (-) with DQB1*02:02. Presence of indicated HLA allele or haplotype is 1, and absence of DRB1*07:01 is 0. OR with 95% CI are presented along with p-values.

HLA: Human leukocyte antigen; N: Number; OR: Odds ratio.