Table 3.
Cost data
| Item | Costs (GBP) | QALY |
|---|---|---|
| Ileocolonoscopy, per procedure | 654.18a | 0.0025 |
| PVCE, per procedure | 800.75a,d | 0.0014 |
| MRE, per procedure | 206.51a | |
| CTE, per procedure | 120.07a | |
| Faecal calprotectin test, per procedure | 123.33a,e | |
| Clinical assessment of symptoms, per procedure | 108e | |
| Infliximab, per year | 5278 (NICE TA187) | 0.00032 |
| Infliximab, administration cost | 225 | |
| Adalimumab, per year | 2860 (NICE TA187) | 0.00052 |
| Adalimumab, administration costs | 0 | |
| Vedolizumab, per year | 24 350 (NICE TA352) | 0.00032 |
| Vedolizumab, administration costs | 310 (NICE TA352) | |
| Corticosteroids, per year | 90 (NICE CG152) | |
| Corticosteroids, administration costs | 0 | |
| Azathioprine, per year | 4 (methotrexate used) | |
| Azathioprine, administration costs | 0 | |
| Inflixmab + azathioprine, per year | 5282 | 0.00032 |
| Infliximab + azathioprine, administration costs | 225 | |
| Remission | 10 | 0.8 [49] |
| Non-active symptomatic | 30 | 0.61 [49] |
| Active symptomatic | 50 | 0.5 [49] |
| Active non-symptomatic | 20 | 0.8 [49] |
| Surgery | 16 583 [1] | 0.022 [50] |
| Abscess drainage | 2569a | |
| Fistula repair | 2951a | |
| Stricturing repair | 2951a | |
| Capsule retention b | 645a | 0.0025c [51] |
| Bowel perforation | 8797a | 0.010 [52] |
CTE, computed tomography enterography; MRE, magnetic resonance enterography; PVCE, pan-intestinal video capsule endoscopy
Reference Cost Collection: National Schedule of Reference Costs, 2016–17—NHS trusts and NHS foundation trusts
5% of capsule retentions are treated as required for surgery.
Removal via push-endoscopy.
Costs include GBP 758.75 for the PVCE procedure and GBP 42 for the patency capsule.
Costs including follow-up attendance with a single gastroenterologist (code 301, NHS England National Prices and Tariffs Workbook 2016/17).