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. Author manuscript; available in PMC: 2020 Oct 1.
Published in final edited form as: Curr Opin Endocr Metab Res. 2019 Aug 29;8:139–144. doi: 10.1016/j.coemr.2019.08.009

Table 1:

Different pathological and molecular characteristics of the human adrenocortical cell lines NCI-H295, SJ-ACC3, MUC-1, CU-ACC1 and CU-ACC2.

Patient Age (y) Patient Gender Tissue Origin SF-1 Status Ki-67 Labeling Index TP53 Status CTNNB1 Status Secr. Funct. Ass. Syndromes
NCI-H295R 48 Female Primary ACC ++ ≈50 % c.782+1_994–1del62740 p.S45P F Unknown
SJ-ACC3 11 Male Primary pediatric ACC ++++++ ≈33–60 % p. G254C WT Li-Fraumeni
MUC-1 24 Male Neck metastasis +++ ≈30 % p.R210fs WT F None
CU-ACC1 66 Female Perinephric metastasis +++ ≈33–60 % WT p.G34R F
CU-ACC2 26 Female Liver metastasis + ≈33–60 % p.G245S WT NF Lynch (Loss of MSH2)