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. 2020 Jun 17;16(6):e1007776. doi: 10.1371/journal.pcbi.1007776

Table 2. Broken symmetry circuits count.

Species Database Nodes Edges SR flip-flop Clocked SR flip-flop JK flip-flop
Nreal Nrand ± SD Z-score Nreal Nrand ± SD Z-score Nreal Nrand ± SD Z-score
Arabidopsis Thaliana ATRM 790 1431 47 1.6 ± 1.2 36.40 3 0.2 ± 0.5 5.80 2 0 ± 0 > 3
Micobacterium tuberculosis Research article 1624 3212 6 1.7 ± 1.4 3.20 0 N/A N/A 0 N/A N/A
Bacillus subtilis SubtiWiki 1717 2609 3 2.1 ± 1.4 0.6 0 N/A N/A 0 N/A N/A
Escherichia coli RegulonDB 879 1835 14 2.1 ± 1.4 8.40 3 0.3 ± 0.8 3.30 0 N/A N/A
Salmonella SL1344 SalmoNet 1622 2852 6 1.4 ± 1.2 3.80 0 N/A N/A 0 N/A N/A
Yeast 27 58 1
YTRP_regulatory 3192 10947 9 5 ± 2.5 1.60 3 3 ± 3.6 0 0 N/A N/A
YTRP_binding 5123 38085 31 21.6 ± 5.8 1.60 192 103.3 ± 45.6 1.90 2 6.8 ± 6.1 -0.8
Mouse TRRUST 2456 7057 82 4 ± 2.1 37.70 216 1.9 ± 2.7 79.50 25 0.004 ± 0.06 417
Human 192 566 90
TRRUST 2718 8215 89 4.3 ± 2.1 40.50 247 3.5 ± 4.8 50.60 45 0.02 ± 0.2 225
TRRUST_2 2862 9396 103 5 ± 2.3 43 319 5.9 ± 7.2 43.20 45 0.02 ± 0.3 150

We report the corresponding Z-score statistics as computed in Table 1.