Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Jun 17;15(6):e0233840. doi: 10.1371/journal.pone.0233840

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication.

PMC Copyright notice

Fig 6 — FluoroSpot IFN-γ, IL2 and IFN-γ+IL2 activities to whole sporozoites were measured pre-immunization (Pre), after each immunization (1, 2, 3, 4, 5) and after CHMI (Post-C); subjects in Cohort 1 only were also measured 7 days after the first immunization (1*). Cohort 1 and Cohort 2 protected and non-protected subjects are shown by indicated symbols. Geometric means are indicated by red bars. Panel A: IFN-γ: Geometric mean activities in both Cohorts significantly rose (p = <0.001) after the first immunization and were higher in Cohort 1 than Cohort 2 after the first and second immunizations (see text). In Cohort 2, activities significantly rose after the fifth immunization. Panel B: IL2: Geometric mean activities in both Cohorts significantly rose (p = <10⁻³) after the first and second (p = <0.01) immunizations and activities of Cohort 1 were significantly higher than Cohort 2 after the first and second immunizations (see text). In Cohort 2, activities significantly rose after the third and fifth immunizations. Panel C: IFN-γ+IL2: Geometric mean activities in both Cohorts 1 were significantly higher after the first immunization, and activities of Cohort 1 were higher than Cohort 2 after the first and second immunizations (see text). In Cohort 2, activities significantly rose after the third and fifth immunizations.